Erasmus Medical Center

This study tests a new way to deliver radiation to kidney tumors using advanced imaging to better target the cancer and avoid healthy kidney tissue. The goal is to preserve kidney function as much as possible. About 40 adults with non-spreading kidney cancer will receive this tre…

This study looks at a new way to treat atrial fibrillation (AFib), a common heart rhythm problem. Doctors will use a special catheter to deliver short electrical pulses to isolate the veins that cause AFib. After 2-3 months, patients will have a second procedure to check if the v…

This study compares two drugs, cyclosporine and methotrexate, to treat moderate-to-severe alopecia areata in children aged 2-17. The goal is to see which medicine works better for regrowing hair and improving quality of life. Participants and their parents choose which treatment …

This study tests whether giving two different chemotherapy and radiation regimens one after the other (total neoadjuvant therapy) works better than standard treatment for patients with esophageal cancer that has spread to nearby lymph nodes. About 216 adults with resectable cance…

This study looks at whether adding a special balloon pump (IABP) to standard ECMO support helps people with severe heart failure recover more quickly. About 430 adults in cardiogenic shock will be randomly assigned to get ECMO alone or ECMO plus the pump. The main goal is to see …

This study tests a device called SCALE-EYE that helps doctors measure the size of polyps during a colonoscopy. It compares SCALE-EYE to the usual method of using biopsy forceps. The goal is to see if SCALE-EYE is accurate and can reduce the number of colonoscopies needed, as well…

This study tests a program called HoorToren that teaches 10-11 year olds how to listen to music safely through headphones. About 600 Dutch children will take part, with half receiving the lessons and half not. Researchers will check if the program changes kids' listening habits a…

This study tests whether giving iron through a vein can improve quality of life and exercise ability in older adults with a narrowed heart valve and low iron levels after a minimally invasive valve replacement. About 400 participants will be randomly assigned to receive either ir…

This study tests whether adding a special sleep and stress program (called RESST) to standard cardiac rehabilitation helps people with heart disease recover better. About 200 adults who have sleep or stress issues will take part. Researchers will track sleep quality, stress level…

This study tests whether a 12-week home-based high-intensity interval training program can improve exercise capacity in people aged 12 to 45 with a congenital heart defect that required a surgical connection between the right heart chamber and lung artery. Participants will be as…

This study looks at whether a home-based computer cognitive training program can help adults with acquired brain injury improve their attention, memory, and daily life. About 30 people receiving outpatient rehab will either do standard therapy or combine it with home computer ses…

This study tests whether playing music during recovery from electroconvulsive therapy (ECT) can reduce postictal agitation—a state of confusion and restlessness. About 92 adults with severe depression will be monitored for agitation after their ECT sessions. If music helps, it co…

This study looks at whether a fast, bedside test can measure fibrinogen levels in trauma patients with severe bleeding within minutes instead of the usual 30-45 minutes. Researchers will test the device on 150 adults arriving at the emergency department with major injuries. The g…

This study looks at whether a small drop of blood from a finger prick can be used to detect tumor DNA in patients with colorectal cancer that has spread to the liver. Researchers will compare results from the finger-prick method with standard blood draws from a vein. If successfu…

This study collects health information from 150 children and adults worldwide who have a rare genetic condition caused by changes in the CAMK2 genes. Researchers will track developmental milestones, seizures, behavior, and social skills to better understand how the disease progre…

This study looks at the puzzling way measles affects the immune system—it can temporarily weaken it, making people more prone to other infections, while also providing lifelong protection against measles itself. Researchers will track 300 adults who either get measles or receive …

This study aims to create a Dental Implant Standard Set that combines patient feedback with clinical results to improve dental implant care. About 1,000 adults aged 18-70 who need dental implants will complete questionnaires at several time points. No risks are involved, and the …

This study looks at whether bright light therapy (BLT) can help reduce depressive symptoms in adults with intellectual disabilities. Many standard treatments are hard to use for this group, but BLT is simple and has shown promise without serious side effects. The study will invol…

This study looks at whether it's possible to send eligible patients home from the hospital early and monitor them remotely using a smartphone app and vital sign checks. The goal is to see if at least 30% of suitable patients can safely transition to this 'virtual ward' under curr…

This study monitors 250 healthcare and animal workers in the Netherlands to catch respiratory viruses early, even in people without symptoms. Researchers will test nose and throat samples and measure immune responses over time. The goal is to spot new or changing viruses and unde…

This study looks at whether people with pulmonary fibrosis can use home monitoring and video calls instead of half their regular clinic visits. The goal is to see if this helps patients manage their own health better. About 220 adults with pulmonary fibrosis will take part, and r…