Erasmus Medical Center

This study is testing a new way to give radiation for kidney cancer that uses advanced imaging to target the tumor more precisely. The goal is to reduce radiation to the healthy part of the kidney, which may help preserve kidney function. About 40 adults with kidney cancer that h…

This study compares two common drugs, cyclosporine and methotrexate, to treat moderate-to-severe alopecia areata in children aged 2-17. Participants and their parents choose which treatment to try, and doctors measure hair regrowth and quality of life over 9 months. The goal is t…

This study tests whether giving two different chemotherapy and radiation regimens one after the other (total neoadjuvant therapy) works better than standard treatment for patients with esophageal cancer that has spread to nearby lymph nodes. About 216 adults with resectable cance…

This study looks at whether adding a special balloon pump (IABP) to standard ECMO support helps people with severe heart failure recover more quickly. About 430 adults in cardiogenic shock will be randomly assigned to get ECMO alone or ECMO plus the pump. The main goal is to see …

This study tests a device called SCALE-EYE that helps doctors measure the size of polyps during a colonoscopy. The goal is to see if it works as well as the standard method (using biopsy forceps) and if it can reduce the number of colonoscopies needed, as well as the waste and ca…

This study tests if a special school program called HoorToren can help children aged 10-11 use headphones and earbuds more safely, to prevent hearing loss. About 600 Dutch primary school children will take part, with some receiving the program and others not. Researchers will mea…

This study tests whether adding a special program for sleep and stress (called RESST) to standard cardiac rehabilitation helps people with heart disease recover better. About 200 adults who have sleep or stress issues will take part. Researchers will measure sleep quality, stress…

This study tests whether playing music during recovery from electroconvulsive therapy (ECT) can reduce postictal agitation—a common side effect where patients become restless or confused. About 92 adults with severe depression will be monitored for agitation after their ECT sessi…

This study tests whether giving iron through a vein can improve quality of life and walking ability in older adults who have iron deficiency and just had a heart valve replacement. About 402 participants will be randomly assigned to receive either iron infusions or standard care.…

This study tests whether a 12-week home-based high intensity interval training program can improve exercise capacity in people aged 12 to 45 with a congenital heart defect that required a surgical connection between the right ventricle and pulmonary artery. Participants will be a…

This study tests whether a home-based computer training program can improve attention, memory, and thinking in people with acquired brain injury (like from a stroke). Thirty adults in outpatient rehab will either get standard care or a mix of weekly in-person sessions plus home c…

This study looks at whether bright light therapy can help reduce depressive symptoms in adults with intellectual disabilities. Many standard treatments are hard to use for this group, but light therapy is simple and has shown promise without serious side effects. The study will t…

This study looks at whether people with pulmonary fibrosis can use home monitoring and video calls instead of half their regular clinic visits. The goal is to see if this helps patients manage their own health better. About 220 adults with pulmonary fibrosis will take part, and r…

This study monitors healthcare and animal workers in the Netherlands for respiratory viruses, including new or changing ones. Researchers will test participants for viruses and measure immune responses, even if they have no symptoms. The goal is to catch outbreaks early and learn…

This study aims to create a Dental Implant Standard Set that combines patient-reported outcomes with clinical measures to better evaluate dental implant success. Researchers will enroll 1,000 patients aged 18-70 across 30 dental practices in the Netherlands and Spain. Participant…

This study looks at whether a quick, bedside test can measure fibrinogen levels in trauma patients with severe bleeding within minutes, instead of the usual 30-45 minute lab wait. Researchers will enroll 150 adults arriving at the emergency department with major bleeding to see i…

This study looks at a new way to treat a common heart rhythm problem called atrial fibrillation (AF). Doctors use a special catheter to zap the veins in the heart with short electrical pulses, aiming to stop the faulty signals that cause AF. In 20 adults, the study will check if …

This study collects health information from 150 children and adults worldwide who have an ultra-rare genetic condition caused by changes in CAMK2 genes. Researchers will track developmental milestones, seizures, and behaviors to create detailed maps of how the disease progresses.…

This study looks at whether a small drop of blood from a finger-prick device can reliably detect tumor DNA in patients with colorectal cancer that has spread to the liver. Researchers will compare results from the finger-prick sample to a standard blood draw from a vein. If succe…

This study looks at whether certain hospital patients can go home early and be cared for remotely using a smartphone app and vital sign monitoring. Researchers want to see if at least 30% of eligible patients can safely use this virtual ward. About 306 adults who are stable enoug…

This study looks at the puzzling way measles affects the immune system—it can temporarily weaken it, making people more prone to other infections, yet also create lifelong protection against measles itself. Researchers will track 300 adults over time to measure changes in immune …