Erasmus Medical Center

This study tests whether giving chemotherapy after surgery can prevent rectal cancer from returning in people who still have cancer DNA in their blood. About 103 adults with high-risk rectal cancer and a positive blood test will either receive chemo or standard monitoring. The go…

This study looks at whether giving extra nutrition through a vein during dialysis (IDPN) helps people on long-term hemodialysis build muscle and maintain healthy blood pressure. Researchers will compare muscle growth rates when patients receive IDPN versus their usual care. The s…

This study compares two medicines, hydroxychloroquine and methotrexate, to see which works better for frontal fibrosing alopecia (FFA), a scarring hair loss that mainly affects women. About 50 adults with FFA who choose one of these treatments will be followed for up to 48 weeks.…

This early-stage trial tests whether a combination of three existing drugs (topiramate, lenalidomide, and pyrimethamine) can wake up dormant HIV hiding in the body and then help the immune system eliminate those infected cells. The goal is to reduce the hidden HIV reservoir, movi…

This study tests if using a special ultrasonic cutting tool (piezosurgery) during jaw surgery causes fewer nerve problems and other complications than traditional saws and drills. About 70 adults having jaw realignment surgery will be randomly assigned to one method or the other.…

This study asks 126 ICU nurses to compare new dialysis bags with current ones used for continuous kidney treatment. Nurses will fill out surveys before and after using the new bags, rating ease of use, safety, and efficiency. The goal is to see if the new design improves daily wo…

This early-stage trial tests a new, custom-made 3D-printed applicator for delivering high-dose radiation (brachytherapy) to cervical cancer. The study will enroll 25 people with locally advanced cervical cancer to see if the device works as intended and is safe. The goal is to le…

This study looks at how a diet low in acid-forming foods (like meat, cheese, and grains) affects kidney function and blood sugar control in people with type 2 diabetes and chronic kidney disease. Researchers will compare a high-acid vs. low-acid diet over 8 weeks in 80 adults, al…

This study looks at 100 children to understand why measles can both suppress the immune system (making them vulnerable to other infections) and also create lifelong immunity to measles itself. Researchers will measure antibodies and immune cells before and after infection to see …

This study looks at whether an artificial intelligence (AI) tool can help doctors decide when it's safe for patients to start early rehabilitation after gastrointestinal or cancer surgery. The tool uses routine hospital data to give a simple yes or no answer. About 103 adults wil…

This study looks at whether an improved endoscopic ultrasound (EUS) procedure can better find cancer in lymph nodes of people with bile duct cancer before they have surgery. About 250 adults with certain types of bile duct cancer that might be removable will get this special ultr…