Erasmus Medical Center

This study compares two common medicines, hydroxychloroquine and methotrexate, to see which works better for frontal fibrosing alopecia (FFA), a scarring hair loss that mainly affects women. Researchers will follow 50 adults who choose one of the treatments for up to 48 weeks, me…

This study tests whether giving chemotherapy after surgery can prevent rectal cancer from returning in people at high risk. Participants must have a positive blood test for cancer DNA after their tumor is removed. About 103 adults will be randomly assigned to receive either stand…

This early-stage trial tests a new, custom-made 3D-printed applicator for delivering internal radiation (brachytherapy) to women with advanced cervical cancer. The study will enroll 25 participants to see if the device can be used safely and effectively. The goal is to improve tr…

This study looks at whether giving extra nutrition through the blood during dialysis helps people on long-term kidney dialysis build muscle. Sixteen adults who have been on dialysis for at least three months will receive either the extra nutrition or standard care. The goal is to…

This study tests whether a combination of three existing drugs (topiramate, lenalidomide, and pyrimethamine) can wake up dormant HIV hiding in the body and help the immune system clear it. 30 adults with well-controlled HIV will receive the drugs in two phases to measure safety a…

This study tests if using a special ultrasonic cutting tool (piezosurgery) during jaw surgery causes fewer nerve injuries and other complications than traditional saws and drills. About 70 adults having jaw realignment surgery will be randomly assigned to one method or the other.…

After gastrointestinal or cancer surgery, it's hard to know when a patient is ready for rehab or discharge. This study tests an AI tool that uses routine hospital data to give a simple yes/no answer to help doctors decide. About 103 adults will take part, and the tool won't repla…

This study looks at whether an improved endoscopic ultrasound (EUS) can better detect cancer in the lymph nodes of people with bile duct cancer before they have surgery. About 250 adults with presumed removable bile duct cancer will get this enhanced EUS. The main goal is to see …

This study looks at how a diet high in acid-forming foods (like meat, cheese, and grains) affects kidney function and blood sugar in people with type 2 diabetes and chronic kidney disease. Researchers will ask 80 participants to follow either a high- or low-acid diet for 8 weeks …

This study uses data from an international registry of 3,000 living liver donors and their recipients to create a more accurate prediction model for transplant outcomes. The goal is to help doctors better counsel patients and improve decision-making for this major surgery. No new…

This study looks at whether a short video can help kidney transplant patients take their medications more accurately than just getting verbal instructions. About 308 adult patients will be split into two groups: one gets the video, the other gets standard verbal teaching. Researc…

This study asks 126 ICU nurses to compare new dialysis bags with the ones currently used for continuous kidney treatment. Nurses will fill out surveys before and after using the new bags to rate ease of use, safety, and efficiency. The goal is to see if the new design is better f…

This study looks at 100 children to understand why measles can both weaken and strengthen the immune system. Researchers will measure antibodies and immune cells before and after infection to see how the virus causes 'immune amnesia.' The goal is to learn more about how measles a…