Chinese Pla General Hospital

This study tests whether adding budesonide capsules early to standard blood-pressure and sugar-lowering drugs can reduce protein leakage in the urine of people with IgA nephropathy, a kidney disease. About 30 adults with newly diagnosed, moderate disease will receive the combinat…

This early-phase study tests a new treatment called EBV-TCR-T cells for people who develop an Epstein-Barr virus (EBV) infection after a stem cell transplant for blood cancer. The therapy uses specially engineered immune cells from the transplant donor to fight the virus. The mai…

This study tests a new treatment called QH101 for people with blood cancers or solid tumors that have not responded to standard therapy. QH101 uses specially engineered immune cells to better recognize and kill cancer cells while avoiding burnout. The trial aims to see if it is s…

This study tests a new approach for hyperthyroidism, where the thyroid is overactive. It combines a minimally invasive heat treatment (thermal ablation) with standard medication. The goal is to see if this combo can better control symptoms like rapid heartbeat and weight loss, wh…

This study tests a new drug called pegmolesatide to see if it can better control anemia in people with chronic kidney disease who are on dialysis. About 240 adults will be split into three groups to compare different treatment plans. The goal is to keep hemoglobin levels in a hea…

This study tests a new combination of drugs (venetoclax, azacitidine, chidamide, and others) against the standard chemotherapy for adults aged 60-75 with newly diagnosed acute myeloid leukemia (AML). The goal is to see if the new regimen leads to more complete remissions and fewe…

This study tests whether adding two drugs (ruxolitinib and chidamide) to the standard chemotherapy before a stem cell transplant can lower the chance of leukemia coming back. It involves 50 people aged 12–65 with high-risk B-cell acute lymphoblastic leukemia who have a suitable d…

This study tests a new treatment called RAK cell therapy, made from human umbilical cord blood, for people with advanced stomach cancer that has spread or come back after standard treatment. The goal is to see if it is safe and helps patients live longer without their cancer grow…

This study tests if a single treatment with umbilical cord stem cells (Amimestrocel) can improve kidney function or reduce protein in the urine of people with diabetic kidney disease. The trial will enroll 120 adults with type 2 diabetes and advanced kidney damage. Researchers wi…

This study tests whether a stem cell therapy called Amimestrocel can help people with acute kidney injury (sudden kidney failure). About 50 adults aged 18-75 will receive the treatment to see if it lowers creatinine levels and reduces the need for dialysis. The goal is to control…

This study tests a new treatment called anti-BCMA-CD19 CAR-T cells for adults with IgG4-related disease that hasn't improved with standard therapies. The treatment involves collecting a patient's own immune cells, modifying them to target the disease, and infusing them back. Rese…

This study tests a new type of metal plate for fixing fresh hip fractures (broken femoral neck). The goal is to see if it helps the bone heal better and with fewer problems than current methods. About 1150 adults who need surgery for this fracture will take part. The main focus i…

This study tests whether giving elderly patients with kidney disease a personalized amount of fluids, guided by a lung water monitor, can prevent acute kidney injury after a heart imaging procedure called coronary angiography. About 320 participants aged 60 and older with chronic…

This study tests whether a new combination of drugs (venetoclax plus CACAG) works better than a standard mix (BAT) for people whose acute myeloid leukemia has come back or hasn't responded to treatment. About 200 adults aged 14 to 75 will take part. The main goal is to see how ma…

This study tests whether adding a GSL synthetase inhibitor (eliglustat) to standard immunotherapy and/or regorafenib can shrink tumors or slow cancer growth in people with advanced colorectal cancer that has not responded to at least two prior treatments. About 120 adults with a …

This study tests whether adding eliglustat (a drug that blocks certain sugar molecules) to standard CD30-targeted immunotherapy can make the treatment work better for people with CD30-positive lymphoma. About 40 adults who have already tried at least one other cancer treatment wi…

This study tests whether adding eculizumab to standard steroid therapy helps people with neuromyelitis optica spectrum disorder (NMOSD) recover better from sudden attacks. About 200 adults with a specific antibody (AQP4-positive) will be followed in real-world clinics. The goal i…

This study tests whether adding the immunotherapy drug camrelizumab to standard chemoradiation can make rectal cancer disappear completely in more patients. About 44 adults with locally advanced rectal cancer will receive the combination before any surgery. The goal is to increas…

This study tests a new drug combination (Chidamide+Decitabine plus an anti-PD-1 antibody) against another standard treatment for people with relapsed or refractory classical Hodgkin lymphoma who cannot or choose not to have a stem cell transplant. The goal is to see if the new co…

This study tests whether adding two drugs (ruxolitinib and decitabine) to the standard chemotherapy given before a stem cell transplant can lower the chance of leukemia returning in high-risk patients. About 200 adults and teens with acute myeloid leukemia in first remission will…

This study compares a new treatment (venetoclax plus CACAG) to standard chemotherapy for people with acute monocytic leukemia. About 204 participants aged 14-60 will be randomly assigned to one of the two groups. The main goal is to see if the new combination leads to more comple…

This study looks at how well ultrasound-guided thermal ablation (using heat to destroy cancer cells) works for people with low-risk papillary thyroid cancer. About 3,700 adults aged 18 to 80 with small tumors (≤2 cm) will be treated and followed for at least a year. Researchers w…

This study tests a new first-line treatment for people with advanced colorectal cancer that cannot be removed by surgery or has spread. The treatment combines two drugs, levozolinate and 5-FU, given together through an IV. The goal is to see if this approach helps control the can…

This study looks at how well ultrasound-guided thermal ablation (using heat to shrink nodules) works for people with benign (non-cancerous) thyroid nodules. Researchers will also create an artificial intelligence model to predict treatment success. About 1500 adults who have symp…

This study compares a new treatment (venetoclax plus the CACAG regimen) to the standard chemotherapy ("3+7") for adults aged 14-75 with newly diagnosed intermediate- or high-risk acute myeloid leukemia (AML). The goal is to see if the new combination leads to more complete remiss…

This study tests a new type of CAR-T cell therapy for adults with B-cell acute lymphoblastic leukemia that has come back or not responded to treatment. The therapy uses donor immune cells that are modified to better target and kill cancer cells while reducing side effects like gr…

This study is testing a new wearable ultrasound sensor that sticks to the skin to help doctors diagnose and monitor conditions like deep vein thrombosis (DVT) and heart failure in real time. About 300 adults with these conditions or those in the ICU will wear the sensor to see ho…

This study is testing a new laser surgery approach for men with small prostates that still cause bothersome urinary symptoms. The goal is to see if combining two laser techniques reduces the risk of the bladder neck tightening after surgery, which can block urine flow. About 426 …

This study looks at whether giving a small amount of the sedative midazolam during surgery can help prevent confusion (delirium) and anxiety in older patients. About 612 people aged 65 to 85 having non-heart, non-brain surgery will be randomly assigned to receive either midazolam…

This study looks at whether a special exercise program (pulmonary rehabilitation) can help people who need high flow oxygen therapy. Researchers will measure muscle strength, breathing, and daily living skills in 70 adults. The goal is to see if rehab can make it easier for patie…

This study tests a new way to treat an enlarged prostate using steam, guided by MRI and ultrasound. The goal is to shrink the prostate and improve urination problems. About 30 men aged 45 to 85 with moderate to severe symptoms will take part. The treatment is an option for those …

This study looks at whether a therapy called OLE (Oscillatory Lung Expansion) helps ICU patients with pneumonia clear mucus from their lungs. Researchers will use a special imaging technique called EIT to see how the lungs respond. The study includes 62 adults in the ICU who prod…

This study is a large survey of over 12,500 Chinese men aged 40 and older. It aims to find out how common lower urinary tract symptoms are and how they affect daily life. Researchers will use questionnaires and tests to gather information. The goal is to better understand the pro…