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Can a new CT scanner see carotid plaques better?

NCT ID NCT07762664

Diagnosis Sponsor: Chinese PLA General Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 13, 2026 · Last updated Aug 21, 2026 · Updated 3 times

Summary

This study compares two types of CT scans for imaging the buildup of plaque in the carotid arteries, which supply blood to the brain. The newer photon-counting detector CT (PCD-CTA) will be compared with the standard energy-integrating detector CT (EID-CTA) in 100 people with carotid artery narrowing. The goal is to see if the newer technology provides clearer, more detailed images of the plaques, which could help doctors better assess stroke risk.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Photon-counting detector CT angiography (PCD-CTA) compared with conventional energy-integrating detector CT angiography (EID-CTA)
What this could lead to
If PCD-CTA proves superior, it could become the preferred imaging method for evaluating carotid plaques, potentially improving stroke risk prediction and treatment planning.
What could go wrong
This is an observational study, not a treatment trial, so it won't directly change patient outcomes. The new technology may not show a clear advantage over current methods in all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 100 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2026

Expected to finish

Jan 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population will consist of patients with carotid atherosclerotic stenosis referred for carotid CT angiography. Eligible participants will be prospectively enrolled before carotid artery intervention.

Ages

10 to 90 years

Sex

Anyone

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18 years or older. * Patients with carotid atherosclerotic plaque or carotid artery stenosis. * Patients scheduled to undergo carotid artery stenting. * Patients undergoing preprocedural carotid CTA examination. * Ability to provide written informed consent. Exclusion Criteria: * Known allergy to iodinated contrast material. * Severe renal insufficiency or other contraindications to contrast-enhanced CT. * Pregnancy or suspected pregnancy. * Severe motion or other artifacts resulting in nondiagnostic image quality. * Incomplete clinical or imaging data.

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Conditions

The condition(s) this trial relates to.

carotid artery disorder carotid stenosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Carotid artery stenosis Carotid atherosclerosis Carotid atherosclerotic plaque

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Chinese PLA General Hospital

    RECRUITING

    Beijing, Beijing Municipality, 100853, China

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