New drug cocktail aims to stop leukemia relapse after transplant

NCT ID NCT07101588

Recruiting now Disease control Sponsor: Chinese PLA General Hospital Source: ClinicalTrials.gov ↗

First seen Mar 20, 2026 · Last updated May 22, 2026 · Updated 10 times

Summary

This study tests whether adding two drugs (ruxolitinib and decitabine) to the standard chemotherapy given before a stem cell transplant can lower the chance of leukemia returning in high-risk patients. About 200 adults and teens with acute myeloid leukemia in first remission will be randomly assigned to receive either the enhanced or standard pre-transplant regimen. The main goal is to see if the new combination improves survival without relapse or severe graft-versus-host disease.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••
Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Chinese PLA General Hospital
RECRUITING

Beijing, Beijing Municipality, 100853, China

Contact Email: •••••@•••••

Conditions

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ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION (HSCT) ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION (HSCT)