Case Comprehensive Cancer Center
Clinical trials sponsored by Case Comprehensive Cancer Center, explained in plain language.
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New chemo cocktail shows promise in leukemia transplant study
Disease control CompletedThis study tested a combination of three chemotherapy drugs (thiotepa, fludarabine, and melphalan) given before a donor stem cell transplant for people with leukemia. The goal was to see if this regimen could help patients stay cancer-free for at least one year after transplant. …
Phase: PHASE2 • Sponsor: Case Comprehensive Cancer Center • Aim: Disease control
Last updated May 26, 2026 04:17 UTC
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New hope for hard-to-treat lung cancers: targeted pill shows promise in early trial
Disease control CompletedThis study tested a pill called abemaciclib in 14 people with advanced lung cancers (small cell, large cell neuroendocrine, and related types) that had stopped responding to chemotherapy. The goal was to see if the drug could shrink tumors and how safe it was. Participants took t…
Phase: PHASE2 • Sponsor: Case Comprehensive Cancer Center • Aim: Disease control
Last updated May 26, 2026 04:15 UTC
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Immunotherapy before surgery shows promise for tough skin cancers
Disease control CompletedThis early-phase study tested whether giving the immunotherapy drug pembrolizumab before surgery could shrink advanced basal cell carcinoma of the head and neck. Thirteen adults with high-risk tumors received the drug, then had surgery to remove any remaining cancer. The goal was…
Phase: PHASE1 • Sponsor: Case Comprehensive Cancer Center • Aim: Disease control
Last updated May 26, 2026 03:58 UTC
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New combo aims to disarm brain tumor's immune shield
Disease control CompletedThis early-phase study tested a combination of two drugs (low dose capecitabine and bevacizumab) in 12 people whose glioblastoma brain tumor had come back. The goal was to see if the treatment could reduce certain immune cells that help the tumor hide from the body's defenses. Th…
Phase: PHASE1 • Sponsor: Case Comprehensive Cancer Center • Aim: Disease control
Last updated May 26, 2026 03:57 UTC
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Can diet and exercise counseling help breast cancer survivors lose weight?
Disease control CompletedThis study tested a personalized nutrition and exercise counseling program for breast cancer survivors who were overweight. The program included both in-person and phone sessions to make it easier to participate. The main goals were to see if participants could lose 10% of their …
Phase: NA • Sponsor: Case Comprehensive Cancer Center • Aim: Disease control
Last updated May 26, 2026 03:56 UTC
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Silent threat: simple office test spots esophagus changes in Symptom-Free patients
Diagnosis CompletedThis study tested a new, quick office-based method to find Barrett's esophagus in people who do not have typical heartburn or acid reflux symptoms. Researchers enrolled 132 adults over age 50 with additional risk factors like being male, white, or having a large waist. The goal w…
Phase: NA • Sponsor: Case Comprehensive Cancer Center • Aim: Diagnosis
Last updated May 26, 2026 03:54 UTC
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Lavender aromatherapy tested to ease anxiety during skin cancer surgery
Symptom relief CompletedThis study tested whether smelling lavender during Mohs surgery for skin cancer helps lower anxiety and reduce the perception of unpleasant odors. 89 adults having surgery on their head or neck took part. Researchers measured anxiety using standard questionnaires and a visual sca…
Phase: NA • Sponsor: Case Comprehensive Cancer Center • Aim: Symptom relief
Last updated May 26, 2026 03:56 UTC
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Quick-Fix light therapy may cut pain without sacrificing results
Symptom relief CompletedThis study tested whether shorter incubation times for a topical gel used in photodynamic therapy (PDT) could reduce pain while still effectively clearing actinic keratoses (precancerous skin spots) on the face. Thirty participants were randomly assigned to have the gel on for 10…
Phase: PHASE2 • Sponsor: Case Comprehensive Cancer Center • Aim: Symptom relief
Last updated May 26, 2026 03:54 UTC
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Gentle touch therapy shows promise for cancer patients
Symptom relief CompletedThis study looked at whether Reiki, a gentle hands-on relaxation therapy, could help cancer patients manage symptoms like pain and fatigue. Ten adults with cancer who had at least three bothersome symptoms received Reiki sessions. The main goal was to see if patients would attend…
Phase: NA • Sponsor: Case Comprehensive Cancer Center • Aim: Symptom relief
Last updated May 22, 2026 14:03 UTC
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Virtual reality goggles ease chemo distress in new study
Symptom relief CompletedThis study tested whether using virtual reality (VR) for 15–30 minutes during a single chemotherapy session could help lower distress, anxiety, depression, and pain. 68 adults with any type of cancer and high distress levels took part. Half used VR with relaxing backgrounds, whil…
Phase: NA • Sponsor: Case Comprehensive Cancer Center • Aim: Symptom relief
Last updated May 19, 2026 11:47 UTC
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New training boosts cancer caregiver confidence
Symptom relief CompletedThis study tested whether an education and support program can help family caregivers of people with cancer feel more confident in their caregiving skills and less anxious. About 484 caregivers and patients took part. Researchers compared different types of support to see which w…
Phase: NA • Sponsor: Case Comprehensive Cancer Center • Aim: Symptom relief
Last updated May 18, 2026 12:11 UTC
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New program boosts colon cancer screening in african american communities
Knowledge-focused CompletedThis study tested an 11-step community program to help African Americans aged 45-75 get screened for colorectal cancer. The program provided education, risk assessment, and help with barriers like finding a doctor, transportation, and costs. 163 participants joined, and the goal …
Phase: NA • Sponsor: Case Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated May 26, 2026 04:22 UTC
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New program aims to boost mammogram rates among homeless women
Knowledge-focused CompletedThis study tested a community-based program to help homeless women get mammograms for breast cancer screening. Researchers worked with 203 women living in shelters or transitional housing to identify and overcome barriers to screening. The goal was to increase screening rates and…
Phase: NA • Sponsor: Case Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated May 26, 2026 04:17 UTC
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Navigator program aims to close cancer care gap for black patients
Knowledge-focused CompletedThis study tested whether a patient navigator could help Black breast and prostate cancer patients complete a shorter course of radiation therapy. 30 African-American adults took part. Researchers used surveys to find out what barriers patients face and whether the navigator help…
Phase: NA • Sponsor: Case Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated May 26, 2026 04:16 UTC
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AI steps in to help breast cancer patients get genetic testing
Knowledge-focused CompletedThis study looked at 35 women with early-stage breast cancer who normally wouldn't qualify for genetic testing. It compared using an artificial intelligence program for pre-test genetic counseling versus the usual in-person session. The goal was to see if AI could help more women…
Phase: NA • Sponsor: Case Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated May 26, 2026 04:11 UTC
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Researchers collect blood from patients with dangerously low platelets
Knowledge-focused CompletedThis study collected one blood sample from 40 adults with very low platelets caused by blood cancer or its treatment. The goal was to gather samples for future research, not to test a new treatment. Participants had platelet counts of 30,000 or lower and were not on blood thinner…
Sponsor: Case Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated May 26, 2026 03:54 UTC
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Breathing device may shield lungs during cancer radiation
Knowledge-focused CompletedThis study looked at whether using a CPAP breathing device during radiation therapy can reduce the amount of radiation reaching the lungs. Eight people with left-sided breast cancer or lung cancer took part. Researchers compared lung radiation doses when patients breathed normall…
Phase: NA • Sponsor: Case Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated May 20, 2026 11:55 UTC
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New camera may predict skin treatment success
Knowledge-focused CompletedThis study tested a new video device that takes images of skin lesions during a light-based treatment for actinic keratoses (precancerous spots). The goal was to see if the device could predict how well the treatment works by measuring certain chemicals in the skin. Fourteen adul…
Phase: PHASE2 • Sponsor: Case Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated May 20, 2026 11:53 UTC