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Immunotherapy before surgery shows promise for tough skin cancers

NCT ID NCT04323202

First seen Nov 01, 2025 · Last updated May 25, 2026 · Updated 28 times

Summary

This early-phase study tested whether giving the immunotherapy drug pembrolizumab before surgery could shrink advanced basal cell carcinoma of the head and neck. Thirteen adults with high-risk tumors received the drug, then had surgery to remove any remaining cancer. The goal was to see if the treatment could reduce tumor size and possibly avoid the need for extensive surgery.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Cleveland Clinic, Case Comprehensive Cancer Center

    Cleveland, Ohio, 44195, United States

Conditions

Explore the condition pages connected to this study.