Case Comprehensive Cancer Center

This study tests if a surgical technique called lymphaticovenous bypass (LVB) can prevent lymphedema (arm swelling) in breast cancer patients who need lymph node removal. About 400 patients with node-positive breast cancer will be randomly assigned to receive standard lymph node …

This study tests whether replacing the intestines or multiple abdominal organs can help people with a rare cancer called pseudomyxoma peritonei (PMP) that has spread in the abdomen and cannot be removed by standard surgery. About 20 participants will receive a transplant and be f…

This study tests an experimental drug called elranatamab for people newly diagnosed with AL amyloidosis, a rare disease where abnormal proteins damage organs. The drug helps the immune system attack the faulty cells causing the disease. About 64 participants will receive injectio…

This study tests whether freezing cancerous tissue with liquid nitrogen before chemotherapy can improve outcomes for people with advanced esophageal cancer. About 40 adults will be randomly assigned to receive either the freezing treatment plus chemo or chemo alone. The freezing …

This study tests a daily digital mindfulness program designed to reduce depressive symptoms in people who have finished treatment for early-stage breast, prostate, or colorectal cancer. About 76 participants will listen to short audio exercises each day for several weeks. The goa…

This study is for people whose cancer has spread to the brain. It compares two types of whole brain radiation: one that avoids the memory center (hippocampus) and one that avoids several brain areas linked to thinking. The goal is to see which approach better protects memory and …

This study tests whether a simple bowel rinsing technique (transanal irrigation) can help people who have bowel control problems after rectal cancer surgery. The study will include 60 adults who recently had surgery and still have a temporary colostomy bag. Researchers want to se…

This study tests whether freeze-dried miracle fruit (MiraBurst) can help improve taste changes caused by cancer treatment in adults with solid tumors. Participants will take one mini-square up to four times a day before meals for 90 days. The goal is to see if it makes food taste…

This study tests whether ChatGPT, an AI chatbot, can help men with localized prostate cancer better understand their pathology results. Fifty participants who recently had a prostate biopsy will use the chatbot to explain their diagnosis and then meet with their doctor. The goal …

This study looks at whether people who have survived cancer have higher levels of fatty acid binding proteins and aging markers in their blood compared to those who never had cancer. Researchers think these higher levels might come from past cancer treatments and could increase t…

This study surveys 240 breast cancer patients (stages I–III) who have had chemotherapy or hormone therapy. The goal is to learn which herbs and supplements people use, how ethnicity influences those choices, and how they might interact with standard treatments. No new treatment i…

This study looks at whether wearable sensors (like smartwatches) and electronic surveys are practical and acceptable for people taking part in early-phase cancer clinical trials. About 30 participants will wear a smartwatch and answer questions through a phone app for 4 weeks. Th…

This study looks at whether taking vitamin D before a light-based treatment (photodynamic therapy, or PDT) can help the immune system fight nonmelanoma skin cancer. About 54 adults who are already scheduled for surgery to remove their skin cancer will take either vitamin D or a p…