Case Comprehensive Cancer Center

This study is testing if freezing cancerous tissue in the esophagus with liquid nitrogen before standard chemotherapy helps patients more than chemotherapy alone. It will involve 40 adults with locally advanced esophageal cancer who are scheduled to receive chemotherapy. Particip…

This study is testing whether transplanting intestines and other abdominal organs can help people with a rare, advanced abdominal cancer called pseudomyxoma peritonei (PMP) when standard surgery is not an option. Up to 20 participants will receive an intestinal or multivisceral t…

This study aims to see if MRI scans taken before surgery can predict whether surgeons will be able to remove all tonsil cancer tissue with clean margins. Researchers will enroll 30 adults with HPV-positive tonsil cancer who are scheduled for robotic surgery. The goal is to help s…

This study is testing if a special microsurgery, called lymphaticovenous bypass (LVB), can prevent a painful and chronic side effect called lymphedema. Lymphedema is arm swelling that affects up to 40% of people after breast cancer surgery to remove lymph nodes. The trial will co…

This study is testing a new, easy-to-use mindfulness program delivered by daily text messages. It aims to help people who have finished treatment for early-stage breast, prostate, or colorectal cancer and are experiencing mild to moderate depression. The goal is to see if this br…

This study is for people whose cancer has spread to the brain. It compares two ways of delivering whole brain radiation therapy, both designed to protect thinking and memory. One method avoids the hippocampus, a key memory area. The other avoids the hippocampus plus several other…

This study is testing a new, faster process for delivering targeted radiation to relieve severe abdominal pain caused by pancreatic cancer. Instead of scheduling a new scan and waiting over a week for a treatment plan, doctors will use a patient's existing diagnostic scan to plan…

This study is testing if a natural product made from freeze-dried miracle fruit can help people who are having taste problems from their cancer treatment. About 45 adults with solid tumor cancers will take the berry product up to four times a day before meals for 90 days. Researc…

This small pilot study aims to see if a larger trial is feasible to test a daily irrigation procedure for people suffering from severe bowel problems after rectal cancer surgery. The procedure, called transanal irrigation, involves using water to help empty the bowel on a schedul…

This study aims to see if taking a probiotic supplement changes the community of bacteria and fungi in the gut and breast tissue of people with breast cancer. Researchers will compare 100 participants, with half taking the probiotic and half taking a placebo, to measure changes i…

This study aims to understand why cancer survivors face higher risks for conditions like diabetes and heart disease later in life. Researchers will compare blood levels of specific proteins and aging markers between 120 cancer survivors and people who never had cancer. The goal i…

This study aims to understand how a light-based treatment, with or without Vitamin D, affects the immune system's response to common skin cancers. Researchers will study adults in Ohio who are already scheduled for skin cancer surgery. Participants may take Vitamin D or a placebo…