Can a daily mindfulness app ease depression in cancer survivors?
NCT ID NCT06811454
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a daily digital mindfulness program designed to reduce depressive symptoms in people who have completed treatment for breast, prostate, or colorectal cancer. Researchers will enroll 76 participants with mild to moderate depression to see if the program is feasible and acceptable. The goal is to offer a simple, accessible tool to improve emotional well-being after a serious illness.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 76 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Aug 2026
An estimate. Start dates often move.
- Expected to finish
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Mar 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Self-reported mild to moderately-severe symptoms of depression (score 5-19 on PHQ-9). 2. A diagnosis of stage 0-III breast, prostate, or colorectal cancer. 3. Completion of primary cancer treatment within 2 years (excludes hormone therapy). 4. An ability to provide informed consent. 5. An ability to read and speak English. 6. Access to a web-enabled device (phone, tablet, computer). Exclusion Criteria: 1. Self-reported minimal and severe depressive symptoms (\<4 and \> 20 on PHQ-9). 2. Self-reported suicidal ideation (\>1 on item 9 PHQ-9). 3. Another psychological, medical, or other condition/issue determined that necessitates priority treatment and/or that would interfere with participation (e.g., schizophrenia, borderline personality disorder) 4. Current or recent substance abuse/dependence. 5. Stage IV cancer diagnosis. 6. A cancer recurrence actively requiring treatment. 7. Self-reported active mindfulness practice. 8. Prior participation in a formal mindfulness program (e.g., MBCT, Mindfulness-Based Stress Reduction Program, Mindfulness-Based Cancer Recovery
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Case Comprehensive Cancer Center, Cleveland Clinic Foundation
Cleveland, Ohio, 44195, United States
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