SYSTEMIC LUPUS ERYTHEMATOSUS

This study tested whether taking coenzyme Q10 supplements can improve health in children with lupus, an autoimmune disease. Sixty kids aged 6-16 with moderate to severe lupus took either CoQ10 plus standard care or standard care alone for 3 months. Researchers measured changes in…

This study tested an experimental drug called cenerimod in 105 adults with active lupus. The goal was to see if the drug could safely reduce certain immune cells that play a role in lupus symptoms. Participants took the drug or a placebo for up to 12 weeks while continuing their …

This early-phase study tested a drug called telitacicept in 16 children (ages 5-17) with lupus. The main goal was to see how the drug moves through the body and to check its safety. This is not a cure, but a step toward better controlling the disease.

This study tested the long-term safety of an experimental drug called BMS-986165 in 261 people with systemic lupus erythematosus (SLE). Participants had already completed a previous study and continued taking the drug to see if any side effects appeared over time. The main goal w…

This study looked at whether tofacitinib, a drug that calms the immune system, is safe and helpful for young adults aged 18 to 45 with moderate to severe lupus skin disease. Thirteen participants took the drug for up to 76 weeks. The main goal was to measure how the body processe…

This study tested whether nipocalimab, an investigational drug, can help people with active systemic lupus erythematosus (SLE) better than a placebo. About 228 adults with SLE took part. The main goal was to see if more people on nipocalimab achieved a meaningful reduction in lup…

This study tested whether the drug hydroxychloroquine can slow or prevent lupus in people who show early signs but do not yet have the disease. 187 participants took either the drug or a placebo for a period of time. Researchers tracked how many developed full lupus and measured …

This study tested a program to help African American adults with lupus manage stress. Thirty participants learned stress-reduction techniques and had their stress levels measured through surveys and saliva samples. The goal was to see if the program could lower stress and improve…

This study looked at over 1,000 people, including sibling pairs and twins where one has a rheumatic disease (like rheumatoid arthritis or lupus) and the other does not. Researchers compared their blood, genes, and environmental exposures to find clues about why one sibling got si…

This study looked at how often people with active lupus take their medication as prescribed. Researchers measured the amount of hydroxychloroquine in the blood of 307 patients to find out who was not taking their medicine. The goal was to understand how common non-adherence is, e…

This study looked at how well a computer-based decision-aid works for people with lupus. The tool helps patients and doctors make shared treatment decisions. Researchers tracked how many eligible patients used the tool and whether clinic staff found it acceptable. The goal was to…

This study looked at how a protein called type 1 interferon, which is high in people with lupus, changes the way the body adapts to exercise. 55 adults with lupus did a 12-week high-intensity aerobic exercise program. Researchers measured changes in fitness and fatigue to underst…

This study looked at how systemic lupus erythematosus (SLE) affects breathing, physical activity, and fatigue. Researchers compared 50 lupus patients to healthy people using lung function tests, a 6-minute walk test, and questionnaires. The goal was to find links between lung hea…

This study looked at 621 adults with moderate to severe systemic lupus erythematosus (SLE) to understand how active their disease is over time. Researchers collected medical records from the past and one follow-up visit to measure disease activity using a standard scoring tool. T…