Sibling rivalry: scientists hunt for clues in rheumatic disease mystery
NCT ID NCT00055055
First seen Nov 01, 2025 · Last updated Jun 16, 2026 · Updated 36 times
Summary
This study looked at families where one sibling has a rheumatic disease (like rheumatoid arthritis or lupus) and the other doesn't. Researchers compared their blood cells, genes, and environmental exposures to find clues about why one got sick. Over 1,000 people took part, including siblings, twins, and healthy volunteers.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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NIEHS Clinical Research Unit (CRU)
Research Triangle Park, North Carolina, United States
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National Institutes of Health Clinical Center
Bethesda, Maryland, 20892, United States
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University of Wisconsin
Madison, Wisconsin, 53792, United States
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.