Pregnancy's secret signals: could tiny molecules explain arthritis and lupus flares?
NCT ID NCT02350491
First seen Feb 03, 2026 · Last updated Jun 20, 2026 · Updated 16 times
Summary
This study looked at how small molecules called microRNAs change during pregnancy in women with rheumatoid arthritis or lupus. Researchers collected blood and urine samples before and after pregnancy from 50 women to see if these changes relate to disease activity. The goal is to find new biomarkers that could predict flares and guide future treatments.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Service de rhumatologie Hôpital de Hautepierre
Strasbourg, 67098, France
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this research could point toward new biomarkers to predict disease flares during pregnancy and identify potential therapeutic targets for rheumatoid arthritis and lupus.
What could go wrong
This is an observational study with only 50 participants, so findings are preliminary and may not lead to direct treatments. The results need validation in larger, more diverse groups.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.