SQUAMOUS CELL CARCINOMA

This study is testing a new, non-surgical approach to treat common skin cancers like basal cell and squamous cell carcinoma. Researchers will use fractional lasers on the cancer spots, followed by a prescription ointment applied for five nights. The goal is to effectively remove …

This study is testing a new approach for people with advanced head and neck cancer. The goal is to see if giving a combination of chemotherapy and immunotherapy before surgery can shrink tumors enough to allow surgeons to perform less extensive operations. This could help patient…

This study is testing whether adding two immunotherapy drugs (tiragolumab and atezolizumab) before and after standard surgery and chemoradiation can better control advanced oral cavity cancer. It is for adults newly diagnosed with a specific type of tumor (PD-L1 positive) that is…

This early-stage study is testing the safety and early effectiveness of an experimental cancer treatment called T3011. The treatment is injected directly into tumors and is being tested both alone and combined with an existing immunotherapy drug (pembrolizumab) in people with adv…

This study is testing whether adding an immunotherapy drug (pembrolizumab) to standard chemotherapy and radiation improves outcomes for people with advanced squamous cell cancer in the nasal cavity or sinuses. The goal is to increase the number of patients whose tumors shrink sig…

This study is testing a new oral medication called NEO212 for adults with specific aggressive brain tumors (like glioblastoma) or brain metastases from other cancers. The main goals are to find a safe and effective dose, see how the body processes the drug, and check if it can he…

This study is testing a personalized cell therapy for adults with advanced non-small cell lung cancer that has stopped responding to standard treatments. Doctors remove a patient's tumor, grow special immune cells from it in a lab, and then infuse a large number of these 'tumor-f…

This program provides access to an experimental drug called AVM0703 for patients with various solid tumors and blood cancers. It is for people who may not have other treatment options. The drug aims to help the body's immune system fight cancer, and early reports show mostly mild…

This study is testing whether the drug afatinib can help control advanced skin cancer that can't be treated with surgery or radiation. It's for people whose cancer has continued to grow despite trying immunotherapy. Researchers will measure if tumors shrink, how long the cancer s…

This study is testing if a special imaging technique used during throat surgery can reduce a common and serious complication called a pharyngocutaneous fistula (a leak in the throat). During surgery, doctors will inject a safe dye and use a special camera to see which throat tiss…

This study is testing a new diagnostic platform called the Italian Tumor Chemogenomic Profiler (IT-TCP). Researchers will analyze tumor samples from 300 patients with various high-risk cancers to see if this detailed analysis can help guide treatment choices. The goal is to see i…

This study is testing whether cancer patients prefer to receive their standard drug treatments at home instead of in a clinic. Researchers want to see if home-based care reduces the burden of travel and improves treatment satisfaction and quality of life for patients. A specializ…

This study asks cancer patients which way they prefer to receive their immunotherapy drugs: as a quick injection under the skin or through a longer IV infusion. Researchers will enroll 480 people with various advanced cancers to compare comfort, convenience, and quality of life b…

This study aims to collect detailed information from 12,000 patients diagnosed with lung and other chest cancers. It will track their health, treatments, and quality of life over many years to understand what factors lead to better or worse outcomes. The goal is to build a powerf…

This study aims to understand the source of pain in oral cancer by comparing how patients and healthy people feel pressure and stretching on the tongue. Researchers will measure pain sensitivity in 40 oral cancer patients and 40 healthy volunteers. The goal is to gather knowledge…

This study aims to understand anal cancer risk in men who have sex with men (MSM) who take medication to prevent HIV. Researchers want to know how common precancerous changes are in this group and test different screening methods to detect them early. The study will also measure …