SQUAMOUS CELL CARCINOMA

This early-phase trial tested whether adding the immunotherapy drug pembrolizumab to standard chemoradiation is safe and effective for people with advanced head and neck cancer. 59 participants received the combination, starting with a pembrolizumab dose one week before chemoradi…

This small study tested an experimental drug called rigosertib in people with a rare, severe form of epidermolysis bullosa (a blistering skin condition) who also developed advanced skin cancer. Only 2 participants were enrolled. The goal was to see if the drug could shrink tumors…

This study tested a new device that delivers targeted radiation to early-stage basal and squamous cell skin cancers without surgery. 36 people aged 60 or older with small, low-risk tumors received treatment. Researchers measured how well the radiation controlled the cancer, side …

This early-phase trial tested a combination of two drugs (IRX-2 regimen and durvalumab) in 19 patients with advanced head and neck cancer that could not be cured with standard treatments. The main goals were to check safety and see if the drugs could boost the immune response ins…

This study tested whether quercetin, a natural compound found in fruits and vegetables, can prevent or delay squamous cell carcinoma (a type of mouth cancer) in people with Fanconi anemia, a rare genetic disorder that raises cancer risk. 48 participants took quercetin pills, and …

This study looked at whether telling people about their genetic risk for melanoma (a serious skin cancer) would make them more careful in the sun. Over 2,000 adults took part, and researchers tracked things like time in the sun, sunscreen use, and sunburns. The goal was to see if…