SQUAMOUS CELL CARCINOMA

This study tests an experimental drug called RP1, which is injected directly into skin cancer tumors. The goal is to see if it can safely shrink or eliminate the cancer before surgical removal. Up to 12 adults with resectable cutaneous squamous cell carcinoma will receive the inj…

This study tests whether adding bavituximab to pembrolizumab can help control advanced head and neck cancer that has stopped responding to standard immunotherapy. The trial includes 7 adults whose cancer has spread or returned and who have already tried platinum chemotherapy and …

This study looks at whether a reduced dose of radiation therapy, combined with the immunotherapy drug nivolumab, can control early-stage HPV-positive throat cancer as well as the standard treatment of radiation plus cisplatin. The trial involves 384 non-smoking participants. The …

This study tests a new drug combination (pembrolizumab plus berahyaluronidase alfa) given as a shot under the skin for Japanese patients with advanced squamous cell skin cancer that has spread or cannot be removed by surgery. The main goal is to see if the treatment shrinks tumor…

This study looks at whether giving lower doses of radiation to a smaller area after robotic surgery can still keep HPV-positive throat cancer from coming back. About 150 adults with early-stage cancer will receive this gentler treatment. The goal is to see if two years later the …

This early-phase trial studies a new treatment for people with advanced esophageal or gastroesophageal cancer who cannot have surgery. It combines a cancer-killing virus (OBP-301) with standard chemotherapy and radiation. The main goal is to check safety and find the best dose, w…

This study looks back at medical records of 72 American Indian patients treated with immunotherapy for different cancers. Researchers want to see how long these patients lived without their cancer getting worse, their overall survival, and side effects compared to White patients.…