PULMONARY DISEASE, CHRONIC OBSTRUCTIVE

This study looked at how well the triple-combination inhaler Trelegy Ellipta works for people with chronic obstructive pulmonary disease (COPD) in real-world settings. Over 12 weeks, 463 adults aged 40 and older with moderate-to-severe symptoms used the inhaler once daily. Resear…

This study tested a 12-week internet-based program for people with COPD who just finished in-hospital rehab. The program used a smartphone app to track activity, provide exercise plans, and offer online lessons, plus regular calls with a therapist. Researchers wanted to see if pa…

This study tested a new drug, 611, in 142 Chinese adults with moderate to severe COPD. The goal was to see if it improves lung function and is safe compared to a placebo over 16 weeks. Participants were aged 40 to 85 and had a history of smoking.

This study tested an investigational drug called vapendavir in 52 adults with COPD (a chronic lung disease). The goal was to see if vapendavir could reduce lower respiratory symptoms like cough, wheezing, and shortness of breath after they were exposed to a common cold virus (rhi…

This study tested whether a single intravenous infusion of PROCHYMAL stem cells is safe and can help people with moderate to severe COPD. 62 participants received either stem cells or a placebo and were followed for two years. The main goals were to check for side effects and mea…

This study looked at whether a simple blood test that finds stray cancer cells (circulating tumor cells) can help detect lung cancer earlier in people at very high risk—smokers over 55 with COPD. About 600 participants had both the blood test and a low-dose CT scan once a year fo…

This study tested a new scoring tool (GLORI-COPD) to see how well it can identify COPD patients at risk of serious complications like lung infections. Researchers enrolled 462 smokers or former smokers aged 35 and older who had not been previously diagnosed with COPD. The goal wa…

This study compared high-flow nasal oxygen (HFNO) to standard noninvasive ventilation for people having a moderate COPD flare-up. 51 adults with COPD and specific blood gas levels took part. The goal was to see if HFNO could improve blood acidity and oxygen levels over 24 hours, …

This study tested whether using nerve blocks with sedation instead of general anesthesia and opioids is safer and provides better pain control for high-risk patients needing an upper leg amputation. The study included 30 adults with conditions like diabetes, heart disease, or lun…

This study tested whether a combination inhaler (Glycopyrrolate/Formoterol) helps people with COPD exercise longer compared to a placebo. 52 participants with stable COPD completed the trial. The main goal was to measure changes in exercise time during a cycling test.

This study tested whether teaching COPD patients simple breathing exercises through short videos could help them feel less short of breath, be more active, and sleep better. Sixty adults with COPD took part, watching 5-7 minute videos and practicing daily for 30 days. Researchers…

This study tested whether an 8-week home program combining physical exercise with brain-training games is feasible for people with COPD. 24 participants aged 50+ tried the program, which aimed to improve both physical and mental function. The main goal was to see if people could …

This study followed 216 people with COPD and at least one other health condition for up to 38 months. Participants used a mobile app to log daily symptoms and other health data. The goal was to find patterns that could predict when a person might have a serious flare-up or get wo…

This study followed 31 adults with COPD for 12 weeks to see how their symptoms, lung function, and markers of inflammation change over time. Researchers measured things like breathing tests, daily symptoms, and blood or sputum markers. The goal was not to test a new treatment, bu…

This study looked at how breathing through a facemask-like resistance affects exercise in people with chronic obstructive pulmonary disease (COPD). 52 volunteers walked on a treadmill with and without added inspiratory resistance. Researchers measured their breathing difficulty a…

This study looked at how the heart and lungs of 10 people with moderate COPD responded during a 30-minute exercise test with short bursts of high-intensity work. Researchers found that lung blood pressure did not rise sharply and heart output stayed steady after the first 5 minut…

This study tested a wearable smart textile sensor system that can monitor heart and lung signals, like ECG and heart sounds. 334 healthy volunteers and people with conditions like high blood pressure or heart disease wore the sensor alongside standard medical devices. The goal wa…

This study tested a new CT-based method to measure bone health and fracture risk in 560 current or former smokers with and without COPD. The goal was to see if detailed bone structure scans could predict fractures better than standard bone density tests. Researchers hope this too…

This study looked at how people with chronic heart failure or COPD process protein from meals. Researchers measured muscle building, body composition, and gut function in 90 adults aged 45 and older. The goal was to understand why these patients lose muscle and weight, so better …

This study looked at whether a wearable sensor could help monitor Chronic Obstructive Pulmonary Disease (COPD) and predict sudden worsening of symptoms, known as exacerbations. 77 people with COPD wore a device for 3 months that tracked things like heart rate, activity, and cough…

This study looked at whether special blood cells called fibrocytes are involved in muscle loss (sarcopenia) in people with COPD. Researchers compared muscle biopsies from 22 COPD patients with and without sarcopenia. The goal was to understand why muscle wasting happens, which co…