Pulmonary disease, chronic obstructive

This trial tests a new approach to pulmonary rehabilitation, a standard programme of exercise and education for people with chronic lung disease. The twist is that informal carers, often family members, join the education and support sessions. The goal is to see if this carer-inc…

This trial is testing an investigational drug called brenipatide in adults with moderate-to-severe COPD. Participants will receive either brenipatide or a placebo for about a year, alongside standard care. The goal is to see if brenipatide improves lung function and reduces the n…

This clinical trial is testing whether an investigational drug called felcorekibart, when added to standard COPD therapy, can reduce the number of moderate and severe flare-ups in adults aged 40 to 80 with moderate to very severe COPD. Participants will receive either felcorekiba…

This study tests whether a nurse navigator program can reduce hospital readmissions in 300 patients who are having hip or knee replacement and also have conditions like heart failure, COPD, or kidney problems. The program provides education and connects patients with their primar…

This study will test whether a pulmonary rehabilitation program that includes inspiratory muscle training (using a device called Powerbreathe) can improve diaphragm function in people with COPD. Researchers will use ultrasound to measure diaphragm movement and thickness before an…