PREDIABETES

This study tests a probiotic called LP-LDL® in 210 adults with prediabetes or type 1 or type 2 diabetes who also have high cholesterol or triglycerides. Participants take either the probiotic or a placebo daily for 12 weeks. Researchers will measure changes in cholesterol, blood …

This study looks at whether eating one medium potato daily as part of a Mediterranean diet affects blood sugar and heart disease risk in adults with prediabetes. About 74 participants will follow either a Mediterranean diet with potatoes or one without for 12 weeks. Researchers w…

This study looks at whether eating proteins and vegetables before carbohydrates (meal sequencing) can improve blood sugar control in 70 adults with diabetes or prediabetes who also experience food insecurity. Participants will receive free produce boxes and either standard nutrit…

This study tests if glucose-lowering drugs (semaglutide and dapagliflozin) can return blood sugar to normal in people with prediabetes and heart disease. About 158 adults will either get the medication plus lifestyle advice or standard care. The goal is to see if treatment can pr…

This small pilot study will test whether bromocriptine, a drug used for other conditions, is safe and tolerable for people with schizophrenia who also have prediabetes. The goal is to see if it can help manage blood sugar problems caused by antipsychotic medications. Fifteen adul…

This study tests whether replacing regular cooking oil with diacylglycerol (DAG) oil for four weeks can improve blood sugar control and metabolism in 40 middle-aged and older adults with prediabetes. Participants will either use DAG oil or regular colza oil while keeping their us…

This study tests whether taking a weekly dose of vitamin D, adjusted to reach a target blood level, can help control blood sugar in 100 adults aged 30-74 with prediabetes. Participants are randomly assigned to receive either vitamin D or a placebo for about 18 months. The main go…

This study looks at whether eating pecans instead of snacks high in bad fats and sugar can improve blood sugar control and heart health in people with prediabetes. About 147 adults aged 25-65 with prediabetes will be split into two groups: one eats 1.5 ounces of pecans daily for …

This study explores whether wearing a continuous glucose monitor (CGM) can motivate people with prediabetes to become more physically active, potentially preventing type 2 diabetes. About 50 adults with prediabetes will wear a CGM for 20 days and receive education on their blood …

This study tests whether a virtual health community can help adults with prediabetes improve blood sugar control and prevent type 2 diabetes. Participants will receive lifestyle guidance, health education, and group support through a digital platform for 6 months. The goal is to …

This study looks at ways to make a diabetes prevention program work better in local health centres. Researchers will test tools like patient reminders and staff training to see if they help more people with prediabetes join and stay in the program. The goal is to improve health o…

This study looks at how muscle cells send tiny packages called extracellular vesicles to fat cells during exercise, which may affect sugar and fat processing. Researchers will compare 80 sedentary adults—some with prediabetes and some healthy—to understand why some people's fat c…

This study looks at whether exercising in the morning or evening helps people with prediabetes control their blood sugar better. Researchers will study 28 adults who are overweight and have an extreme natural body clock. Each person will try no exercise, morning exercise, and eve…

This study uses a special, high-frequency ultrasound to look at the walls of arteries in people with prediabetes. The goal is to detect very early signs of blood vessel damage that standard tests might miss. Researchers will measure the thickness of artery layers in 1,740 partici…

This study will enroll 1,000 adults at high risk for diabetes to test whether continuous glucose monitors combined with artificial intelligence can detect prediabetes earlier and more accurately than current methods. Participants will wear a glucose monitor and provide other heal…

This study looks at how artificial sweeteners (saccharin, sucralose) and a natural one (erythritol) affect blood sugar control, blood clotting, and heart disease risk in 80 adults with prediabetes. Participants will be assigned to one of four groups and consume a sweetener or wat…

This study is testing a new, noninvasive device called the Argus CGM that uses light and AI to estimate blood sugar levels without needles or skin punctures. Up to 100 adults with type 1 diabetes, type 2 diabetes, or prediabetes will wear the device for 15 days while researchers …

This study aims to understand prediabetes in young adults and how it relates to other health issues like insulin resistance, high cholesterol, and fatty liver. Researchers will study 120 people with prediabetes at Assiut University Hospital through exams and lab tests. The goal i…