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Sugar substitutes under scrutiny: new study targets heart risks in prediabetes

NCT ID NCT07377097

First seen Jan 31, 2026 · Last updated May 22, 2026 · Updated 16 times

Summary

This study looks at how artificial sweeteners (saccharin, sucralose) and a natural one (erythritol) affect blood sugar control, blood clotting, and heart disease risk in 80 adults with prediabetes. Participants will be assigned to one of four groups and consume a sweetener or water for two weeks. Researchers will measure changes in glucose tolerance, gut bacteria, and immune cell function to understand if these sweeteners are safe for people at risk for diabetes and heart disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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