POSTOPERATIVE PAIN MANAGEMENT

This study compares two ways of giving a nerve block (erector spinae plane block) to control pain after lumbar fusion surgery. Sixty adults undergoing back surgery will be randomly assigned to receive either a single-level or a two-level injection. Researchers will measure pain s…

This study compares two pain-relief methods for adults having open inguinal hernia repair: an ultrasound-guided nerve block (TFPB) versus surgical wound infiltration with local anesthetic. The goal is to see which method reduces opioid use and improves pain scores and recovery. 1…

This study will observe 120 adults undergoing video-assisted thoracoscopic surgery (VATS) to compare three pain management approaches: a nerve block (SPSIPB), an epidural, and standard opioid painkillers. Researchers will measure pain scores and how much extra pain medicine patie…

This study compares two pain-blocking methods for people having total knee replacement. One group gets a standard adductor canal block, while the other gets that plus an extra block targeting the biceps femoris short head muscle. Researchers will measure pain scores and how much …

This study compares two types of nerve blocks (ESP and RLB) given right after a C-section to see which one helps women recover better. Researchers will look at pain, comfort, and overall recovery in 60 women using a special questionnaire. The goal is to find the best way to manag…

This study tests whether placing small beads containing an antibiotic and painkillers directly into the surgical site during spine surgery can improve recovery. About 100 adults having elective lumbar fusion will be randomly assigned to get beads with or without added pain medici…

This study tests whether a new painkiller called suzetrigine can help people use fewer opioids after ACL surgery while still controlling pain. About 140 participants will receive either suzetrigine or standard opioid-based pain care and report their pain, opioid use, and side eff…

This study compares three common pain relief methods for people having laparoscopic gallbladder surgery: numbing the surgical area with bupivacaine, a nerve block in the back (ESP block), or a small dose of morphine into the spinal fluid. The goal is to see which method reduces p…

This study tests a non-invasive device that gently stimulates a nerve in the ear to see if it can reduce pain and the need for strong painkillers after complex spinal surgery. About 98 adults having major back surgery will be randomly assigned to receive either the real stimulati…

This study compares two drug combinations given through an IV to manage pain after vaginal hysterectomy. 50 women will receive either dexmedetomidine alone or with ketamine. The goal is to see which provides better pain relief and reduces the need for extra painkillers in the fir…

This study looks at three different ways to give methadone during heart surgery to find the best dose for controlling pain afterward. About 69 adults having planned heart surgery will take part. Researchers will measure methadone levels in the blood and ask about pain to see whic…

This study will track opioid use in 35 adults undergoing thoracotomy (chest surgery) to understand how pain medications affect recovery. Researchers will measure pain levels at several time points and look at complications and hospital stay length. The goal is to find better ways…

This study looks at 30 older adults (65+) having lung surgery with one-lung ventilation. Researchers will measure brain oxygen levels during surgery and test thinking and pain afterward. The goal is to see if low brain oxygen is linked to confusion and worse pain, which could hel…

This study looks at how well ankle numbing (ankle block) works in people with and without diabetes during foot or ankle surgery. Researchers will measure how fast the numbing starts, how much pain medicine is needed afterward, and if blood sugar control plays a role. The goal is …

This study looks at 50 children aged 1-18 having penile surgery to find the best place and depth for a pudendal nerve block. Doctors will measure how far from the anus and how deep the needle needs to go, and see if that relates to the child's age, height, and weight. The goal is…