POSTOPERATIVE PAIN MANAGEMENT

This study tests whether a non-invasive device that gently stimulates a nerve in the ear can lower inflammation and pain after major spine surgery. About 50 adults having long-segment spinal fusion will be randomly assigned to receive the stimulation or standard care. Researchers…

This study looks for the smallest amount of a numbing medicine (bupivacaine) that works well for pain after lung surgery. About 27 adults having planned lung surgery will get a nerve block before the procedure, and the dose will be adjusted based on how well it works. The goal is…

This study looks at whether teaching people about how pain works (pain neuroscience education) can improve recovery after rotator cuff surgery. About 45 adults aged 40-75 with medium-sized tears will be split into three groups: standard rehab, rehab plus pain education before sur…

This study tests two different ultrasound-guided pain blocks given before lumbar microdiscectomy surgery. The goal is to see which block reduces the need for strong painkillers (opioids) and improves recovery in the first two days after surgery. 80 adults aged 18-65 will take par…

This study compares two types of nerve blocks—the newer iliopsoas block (IPB) and the established PENG block—for pain control after hip replacement surgery. 118 adults will receive one of the blocks before surgery, and researchers will measure pain during movement 6 hours after t…

This study tests two different pain-blocking methods (iPACK and BiFeS) for people having knee replacement surgery. The goal is to see which one provides better pain relief and helps patients recover faster. About 74 adults will take part, and all will receive a standard nerve blo…

This study tests two different pain medicines (dezocine or nalbuphine) given with a standard opioid after oral cancer surgery involving flap reconstruction. The goal is to see which combination provides better pain relief with fewer side effects, and whether it helps the surgical…

This study compares two types of nerve blocks (rhomboid intercostal and serratus posterior superior) to see which one provides better pain relief after video-assisted lung surgery. Forty adults scheduled for lung surgery will be enrolled. The goal is to find the most effective te…

This study tests whether giving a combination of two drugs (lidocaine and dexmedetomidine) during weight-loss surgery can lower pain, inflammation, and cell stress afterward. About 104 adults having laparoscopic bariatric surgery will be randomly assigned to receive the combo, on…

This study tests whether a drug called Anrikefon can control pain after eye surgery as well as a standard painkiller, but with fewer side effects like drowsiness. About 204 adults having eye surgery under general anesthesia will receive either Anrikefon or the standard drug durin…

This study looks at two ways to manage pain after umbilical hernia surgery: a single-dose epidural block and an ultrasound-guided TAP block. Researchers will measure pain levels at different times after surgery to find out which method works better. The goal is to improve pain co…

This study tests a new medicine called HSK21542 for pain after hip replacement surgery. About 405 adults will receive either the new drug, morphine, or a placebo. The goal is to see if HSK21542 controls pain better and causes fewer side effects like nausea and vomiting.

This study tests two different numbing injections (nerve blocks) to see which one controls pain better after coronary artery bypass surgery. About 64 adults aged 45-85 having planned heart bypass will receive one of the two blocks before surgery. The goal is to find which block r…

This study looks at whether taking sitz baths (sitting in warm water) after surgery for pelvic organ prolapse can help reduce pain and improve recovery. About 112 women will be randomly assigned to either use sitz baths or follow standard care. The main goal is to measure pain le…

This study compares two sedative medications, remimazolam and midazolam, in adults aged 65 and older having orthopedic surgery with regional anesthesia. The goal is to see which drug provides better sedation during the procedure and causes fewer thinking or memory problems shortl…

This study looks at whether adding a TAP block (a numbing injection in the belly wall) to standard spinal morphine helps women feel better and recover faster after a planned C-section. About 150 mothers will take part, with half getting the extra block. Researchers will measure r…

This study compares two pain relief methods for women having laparoscopic hysterectomy: a spinal injection of morphine versus numbing medicine injected into the belly and surgical sites. The goal is to see which approach provides better recovery, less pain, and fewer side effects…

This study looks at whether adding dexmedetomidine to a standard numbing medicine (ropivacaine) in a nerve block can improve pain control after hip replacement surgery. About 120 adults having hip surgery will be randomly assigned to receive either the standard nerve block or the…

This study looks at whether using ultrasound-guided nerve blocks for pain relief after major abdominal surgery can lower the chance of lung complications. It will follow 500 adults aged 65 and older who are having elective surgery. The choice of pain management is made by the car…

This study looks at two different numbing techniques used during gallbladder removal surgery. Researchers will map exactly which areas of skin become numb with each method. The goal is to understand how these blocks work so doctors can better manage pain after surgery. About 40 a…