POSTOPERATIVE PAIN MANAGEMENT

This study looks at three different pain relief methods for people having gallbladder removal surgery. The goal is to find which method reduces pain and the need for strong opioid drugs the most. About 132 adults will be randomly assigned to receive either a local numbing injecti…

This study tests whether giving a nerve block at one or two spots in the back provides better pain control after lumbar fusion surgery. Sixty adults having this surgery will be randomly assigned to receive either a single or double injection of numbing medicine. Researchers will …

This study compares a new pain medicine called Suzetrigine to standard opioid painkillers for people recovering from common sports surgeries like ACL repair. The goal is to see if Suzetrigine can control pain just as well while reducing the amount of opioids needed. About 140 par…

This study tests two pain-blocking methods after open inguinal hernia surgery: an ultrasound-guided nerve block versus numbing the surgical wound directly. About 104 adults will be randomly assigned to one of the two groups. The goal is to see which approach reduces the need for …

This study tests a non-invasive device that gently stimulates a nerve in the ear to see if it can reduce pain and the need for strong painkillers after complex spinal surgery. About 98 adults having major back surgery will be randomly assigned to receive either the real stimulati…

This study compares two ways to manage pain after total knee replacement surgery. One group gets a standard nerve block (adductor canal block), and the other gets that block plus an additional block (biceps femoris short head block). The goal is to see if the combination provides…

This study looks at two types of pain blocks (ESP and RLB) given after a C-section to see which one helps women recover better. About 60 women will have their recovery quality checked 24 hours after surgery using a special questionnaire. The goal is to find the best way to manage…

This study looks at 120 adults having keyhole lung surgery to see which pain relief method works best: a nerve block, an epidural, or standard painkillers. Researchers will measure pain scores and how much extra pain medicine is needed in the first 24 hours. The goal is to find t…

This study compares two drug combinations given through an IV to manage pain after vaginal hysterectomy. 50 women will receive either dexmedetomidine alone or with ketamine. The goal is to see which provides better pain relief and reduces the need for extra painkillers in the fir…

This study tests whether placing small beads containing an antibiotic and pain relievers directly into the surgical site during spine surgery can improve recovery. About 100 adults having elective lumbar fusion will be randomly assigned to get beads with or without added pain med…

This study looks at three different ways to give methadone during heart surgery to find the best dose for controlling pain afterward. About 69 adults having planned heart surgery will take part. Researchers will measure methadone levels in the blood and ask about pain to see whic…

This study looks at how a numbing shot around the ankle (ankle block) works in people with and without diabetes who are having foot or ankle surgery. Researchers will measure how fast the numbness starts, how much pain medicine is needed after surgery, and if blood sugar control …

This study looks at how much pain medicine (opioids) patients need after chest surgery and what affects their pain. Researchers will track 35 adults having thoracotomy to find links between opioid use, complications, and hospital stay. The goal is to improve pain management and r…

This study watches 30 older adults (65+) having lung surgery with one-lung breathing to see if drops in brain oxygen affect their memory, thinking, and pain afterward. Researchers measure brain oxygen during surgery and test thinking before and after. The goal is to learn how to …

This study looks at 50 children aged 1-18 having penile surgery to find the best place and depth for a pudendal nerve block. Doctors will measure how far from the anus and how deep the needle needs to go, and see if that relates to the child's age, height, and weight. The goal is…