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Brain oxygen dips during lung surgery may cloud thinking in seniors

NCT ID NCT07339124

Knowledge-focused Sponsor: Ankara Ataturk Sanatorium Training and Research Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at 30 older adults (65+) having lung surgery with one-lung ventilation. Researchers will measure brain oxygen levels during surgery and test thinking and pain afterward. The goal is to see if low brain oxygen is linked to confusion and worse pain, which could help doctors improve care for elderly patients.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help doctors better monitor brain oxygen during lung surgery to reduce confusion and improve pain control in older patients.
What could go wrong
This is a small observational study with only 30 patients, so results may not apply to everyone. It does not test a new treatment, only measures existing care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 30 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jan 2026

An estimate. Start dates often move.

Expected to finish

Oct 2026

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

This study will be conducted in accordance with the Helsinki Declaration and will take place at SBÜ Ankara Atatürk Sanatorium Training and Research Hospital after obtaining ethical committee approval. The study will be planned for geriatric patients over 65 years of age with a high school diploma or higher education level who have given informed consent and are scheduled for single-lung ventilation (TAV) with standard anesthesia monitoring

Ages

65 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients aged 65 and over with a high school diploma or higher education * Patients undergoing lung resection via thoracotomy (wedge resection, lingulectomy, segmentectomy, lobectomy, pneumonectomy) * American Society of Anesthesiologists (ASA) score I-II-III, * Body mass index (BMI) between 18-40 kg/m2, * Patients undergoing surgery under general anesthesia will be included in the study. Exclusion Criteria: * Patients under 65 years of age, patients over 65 who are illiterate, * Who have completed primary or secondary school, * Patients with pre-existing cognitive impairment confirmed by preoperative Mini Mental State Examination (MMSE), * Patients with a history of previously diagnosed mental illness, cerebrovascular disease, senile dementia, stroke, * Patients using continuous anti-inflammatory/analgesic medications, * Patients with preoperative chronic pain, * Severe cardiovascular disease, * Diagnosed neurological and psychiatric diseases, * Patients allergic to the anesthetic and analgesic drugs to be administered, * Patients with severe renal failure, gastrointestinal ulceration or severe asthma that prevents the administration of standard analgesia protocols, * Patients undergoing surgery other than lung resection, * Patients undergoing surgery with TIVA (total intravenous anesthesia) will be excluded from the study.

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative Postoperative Cognitive Complications

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Geriatric anesthesia One lung ventillation (OLV) Pocd - postoperative cognitive dysfunction Postoperative pain management Thoracic anesthesia

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

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Contacts and locations

Locations

  • Ankara Ataturk Sanatorium Training and Research Hospital

    Ankara, Turkey (Türkiye)

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