New study tests two injections to ease knee surgery pain and cut opioid use
NCT ID NCT07643883
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at 60 people having total knee replacement surgery to see which of two nerve blocks works better for pain control when added to a standard block. One block targets the space behind the knee (IPACK), the other targets a muscle plane (AMM). The goal was to reduce pain and the need for opioid painkillers after surgery.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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60 people
The number who actually took part.
- Started
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Oct 2023
- Finished
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Feb 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 75 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Anesthesiologists (ASA) physical status I-II-III * Total Knee Arthroplasty Surgery Exclusion Criteria: * cardiovascular disease, * hepatic dysfunction, * coagulopathy or current use of anticoagulant therapy, * inability to cooperate, * known allergy to any of the study medications, * refusal to participate in the study
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Ataturk University
Erzurum, 25000, Turkey (Türkiye)
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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