New study tests better pain control after hernia surgery
NCT ID NCT07238829
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two ways to manage pain after open inguinal hernia repair: an ultrasound-guided nerve block (TFPB) versus surgical wound infiltration with local anesthetic. About 104 adults will be randomly assigned to one method. The goal is to see which reduces opioid use and improves pain scores and recovery in the first 24 hours after surgery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- local anesthetic (bupivacaine)
- What this could lead to
- If one method works better, it could lead to less opioid use and better pain control after hernia surgery.
- What could go wrong
- This is a small, early-stage trial with only 104 participants. Results may not apply to all patients or surgeries.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 104 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jan 2027
An estimate. Start dates often move.
- Expected to finish
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Apr 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥ 18 years * Scheduled for elective unilateral open inguinal hernia repair * Planned anesthesia: spinal anesthesia * American Society of Anesthesiologists (ASA) physical status I-II * Able to understand the study procedures and provide written informed consent Exclusion Criteria: * Body mass index (BMI) \> 35 kg/m² * Known hypersensitivity to local anesthetics used in the study (e.g., bupivacaine) or to analgesic medications * Coagulopathy * Infection or hematoma at the planned block site * Significant systemic disease (such as chronic kidney disease, hepatic failure, chronic obstructive pulmonary disease, etc.) * History of chronic pain or long-term analgesic use * Inability to use the patient-controlled analgesia system * Presence of psychiatric disorders * Refusal to participate in the study. * Cases with a surgical duration shorter than 30 minutes or longer than 180 minutes were excluded.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
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Other studies related to the condition(s) this trial covers.
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