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Which painkiller is best after keyhole lung surgery? new study aims to find out

NCT ID NCT07238348

Symptom relief Sponsor: Karadeniz Technical University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study will observe 120 adults undergoing video-assisted thoracoscopic surgery (VATS) to compare three pain management approaches: a nerve block (SPSIPB), an epidural, and standard opioid painkillers. Researchers will measure pain scores and how much extra pain medicine patients need in the first 24 hours after surgery. The goal is to identify which method provides the best pain relief with the fewest side effects.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Serratus Posterior Superior Intercostal Plane Block (SPSIPB), Thoracic Epidural Analgesia (TEA), systemic opioid analgesia
What this could lead to
If this study succeeds, it could point to a better, safer way to manage pain after minimally invasive lung surgery, potentially reducing opioid use and side effects.
What could go wrong
This is an observational study, not a randomized trial, so results may be less definitive. It is also small (120 people) and hasn't started yet, so findings may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 120 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Dec 2025

An estimate. Start dates often move.

Expected to finish

Aug 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult patients (18-75 years) undergoing elective video-assisted thoracoscopic surgery (VATS) under general anesthesia at a tertiary university hospital. Patients will receive SPSIPB, thoracic epidural analgesia, or systemic opioid analgesia as part of routine clinical practice, and will be followed for postoperative pain outcomes within the first 24 hours.

Ages

18 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18-75 years * Scheduled for elective video-assisted thoracoscopic surgery (VATS) * ASA physical status I-III * Ability to understand study procedures and provide written informed consent * Hemodynamically stable preoperatively Exclusion Criteria: * Known allergy or contraindication to local anesthetics or study medications * Coagulopathy or use of anticoagulants not suitable for regional anesthesia * Local infection or skin lesions at the injection site * Severe pulmonary disease (e.g., severe COPD, uncontrolled asthma) * Chronic opioid use or chronic pain disorders * Neurological or psychiatric disorders impairing cooperation * Pregnancy or breastfeeding * BMI \> 35 kg/m² * Conversion from VATS to thoracotomy * Inability to comply with postoperative assessments

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Conditions

The condition(s) this trial relates to.

agnosia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Postoperative pain management Serratus posterior superior intercostal plane block Thoracic epidural analgesia Video-assisted thoracoscopic surgery (VATS)

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  2. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

More trials for these conditions

Other studies related to the condition(s) this trial covers.