POSTOPERATIVE PAIN MANAGEMENT

This study tests whether a non-invasive device that gently stimulates a nerve in the ear can lower inflammation and pain after major spine surgery. About 50 adults having long-segment spinal fusion will be randomly assigned to receive the stimulation or standard care. Researchers…

This study compares two painkiller combinations—dezocine plus sufentanil versus nalbuphine plus sufentanil—for pain relief after oral cancer surgery with flap reconstruction. Sixty adults will receive one of the two combinations through a patient-controlled pump. The goal is to s…

This study is testing different amounts of the numbing medicine bupivacaine to find the smallest dose that still works for a nerve block after lung surgery. About 27 adults having video-assisted lung surgery will get an ultrasound-guided nerve block before surgery, and the dose w…

This study looks at whether adding a TAP block (a type of nerve block) to standard pain relief helps women recover better after a planned C-section. 150 women will be observed: some get the TAP block, others don't. Researchers will measure recovery quality, pain levels, and how s…

This phase 3 trial tests a new drug called HSK21542 for pain after orthopedic surgery like hip replacement. About 405 adults will receive either HSK21542, morphine, or a placebo. The goal is to see how well it controls pain and what side effects occur.

This study compares two types of nerve blocks (ESPB and SPSIPB) to see which provides better pain relief after coronary artery bypass surgery. About 64 adults aged 45-85 will receive one of the blocks before surgery, and their pain levels, opioid use, and recovery speed will be t…

This study tests whether giving a combination of two drugs (lidocaine and dexmedetomidine) during weight-loss surgery can reduce pain, inflammation, and cell stress afterward. About 104 adults having laparoscopic bariatric surgery will receive either the combo, one drug alone, or…

This study tests two sedative drugs, remimazolam and midazolam, in adults aged 65 and older having orthopedic surgery with regional anesthesia. The goal is to see which drug provides better sedation during surgery and causes fewer problems with thinking and memory shortly after. …

This study compares two types of nerve blocks (IPB and PENG) for pain control after hip replacement surgery. 118 adults will be randomly assigned to receive one block before surgery. The main goal is to see if the newer IPB block works as well as the PENG block for reducing pain …

This study compares two types of nerve blocks—rhomboid intercostal and serratus posterior superior—to see which one controls pain better after video-assisted lung surgery. Forty adults having elective wedge resection or biopsy will receive one of the blocks with bupivacaine. Thei…

This study tests whether adding dexmedetomidine to a standard numbing shot (ropivacaine) improves pain control after hip replacement surgery. About 120 adults will receive either the combo or the numbing shot alone. Researchers will measure how long pain relief lasts and how much…

This study tests whether adding pain neuroscience education (PNE) to standard rehab improves pain, function, and fear of movement in 45 adults aged 40-75 recovering from rotator cuff tear surgery. Participants are randomly assigned to standard rehab alone, PNE before surgery, or …

This study tests two different ways to numb the back of the knee after total knee replacement surgery. Both methods are combined with a standard front-of-thigh block. The goal is to see which approach leads to better overall recovery, less pain, and less need for strong painkille…

This study compares two types of ultrasound-guided nerve blocks given before lumbar microdiscectomy (a type of back surgery) to see which one provides better pain relief. Eighty adults aged 18-65 will be randomly assigned to receive one of the two blocks. The main goal is to meas…

This study tests whether a drug called Anrikefon can control pain after eye surgery as well as a standard painkiller, but with fewer side effects like drowsiness. About 204 adults having eye surgery under general anesthesia will receive either Anrikefon or the standard drug durin…

This study looks at two ways to manage pain after umbilical hernia surgery: a single-dose epidural block and an ultrasound-guided TAP block. Researchers will measure pain levels at different times after surgery to find out which method works better. The goal is to improve pain co…

This study looks at whether taking sitz baths (sitting in warm water) after surgery for pelvic organ prolapse can help reduce pain and improve recovery. About 112 women will be randomly assigned to either use sitz baths or follow standard care. The main goal is to measure pain le…

This study compares two pain relief methods for women having laparoscopic hysterectomy: a spinal injection of morphine versus numbing medicine injected into the belly and surgical sites. The goal is to see which approach provides better recovery, less pain, and fewer side effects…

This study looks at whether ultrasound-guided nerve blocks can lower the chance of lung complications after major abdominal surgery. Researchers will observe 500 adults aged 65 and older who are having elective surgery. The study does not assign treatments—it simply watches what …

This study looks at two different nerve blocks used to manage pain after gallbladder removal surgery. Researchers will map where on the skin each block causes numbness and see which one covers the surgical cuts better. The goal is to learn more about these blocks to improve pain …