New nerve block technique could ease pain after knee surgery
NCT ID NCT07248072
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests two different ways to numb the back of the knee after total knee replacement surgery. Both methods are combined with a standard front-of-thigh block. The goal is to see which approach leads to better overall recovery, less pain, and less need for strong painkillers. About 74 adults having knee replacement will take part.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 74 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Dec 2025
- Expected to finish
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Jul 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 75 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 18-75 years * Scheduled for elective primary unilateral total knee arthroplasty (TKA) * Planned spinal anesthesia * ASA physical status I-III * Ability to understand study procedures and provide written informed consent Exclusion Criteria: * Known allergy or hypersensitivity to local anesthetics or other study medications * Coagulopathy or current anticoagulant therapy * Severe hepatic, renal, or cardiac failure * History of neuropathic pain * Infection at the site of proposed nerve block * Pre-existing neuromuscular disorders in the lower extremities * Inability to cooperate or refusal to participate in the study * Pregnancy
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Ataturk University
RECRUITINGErzurum, 25000, Turkey (Türkiye)
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