Small study aims to pinpoint best dose for Post-Surgery pain block
NCT ID NCT07446959
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study is testing different amounts of the numbing medicine bupivacaine to find the smallest dose that still works for a nerve block after lung surgery. About 27 adults having video-assisted lung surgery will get an ultrasound-guided nerve block before surgery, and the dose will be adjusted up or down based on how well it controls pain. The goal is to improve pain relief while using as little medicine as possible.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- bupivacaine
- What this could lead to
- If successful, this could help doctors use the smallest effective dose of painkiller for a specific nerve block, improving pain control after lung surgery while reducing side effects.
- What could go wrong
- This is a very small, early-phase study (27 people) that only finds the dose for 50% of patients, not a proven treatment. Results may not apply to all surgeries or patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 27 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Mar 2026
- Expected to finish
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Jul 2026
An estimate. End dates often move.
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 18 years or older * Scheduled for elective video-assisted thoracoscopic surgery (VATS) * American Society of Anesthesiologists (ASA) physical status I-III * Planned to receive ultrasound-guided serratus posterior superior intercostal plane block for postoperative analgesia * Ability to provide written informed consent Exclusion Criteria: * Refusal to participate in the study * Known allergy or contraindication to local anesthetics * Infection at the block injection site * Coagulation disorders or anticoagulant therapy contraindicating regional anesthesia * Severe respiratory insufficiency * Chronic opioid use or chronic pain syndrome * Pregnancy * Inability to cooperate or communicate postoperative pain scores
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Genom att skicka in godkänner du våra Användarvillkor
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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T.C. Sağlık Bakanlığı Bursa Şehir Hastanesi
RECRUITINGBursa, 16250, Turkey (Türkiye)
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