Double nerve block may ease knee surgery pain
NCT ID NCT07233785
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two pain-blocking methods for people having total knee replacement. One group gets a standard adductor canal block, while the other gets that plus an extra block targeting the biceps femoris short head muscle. Researchers will measure pain scores and how much extra pain medication is needed. The goal is to see if the combination provides better pain control.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- bupivacaine
- What this could lead to
- If it works, this could provide better pain relief after knee replacement surgery, reducing the need for strong painkillers.
- What could go wrong
- This is a small, early-stage trial with only 60 participants, so results may not apply to everyone. The added block may not provide significant extra benefit.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Nov 2025
An estimate. Start dates often move.
- Expected to finish
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Nov 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adult patients over 18 years of age who underwent percutaneous nephrolithotomy under general anesthesia and were I-II-III according to the American Society of Anesthesiologists (ASA) risk classification were included in the study. Exclusion Criteria: * patients who did not give consent, * patients with coagulopathy, * patients with signs of infection at the block application site, * patients using anticoagulants, * patients with known allergies to any of the study drugs, * patients with unstable hemodynamics, * patients who could not cooperate during postoperative pain assessment * patients who wanted to withdraw from the study, * patients with alcohol and drug addiction, * patients with musculoskeletal abnormalitie
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Sivas Cumhuriyet University School of Medicine, Anesthesiology and Reanimation
Sivas, Sivas, 58140, Turkey (Türkiye)
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- New study tests two injections to ease knee surgery pain and cut opioid use
- Eye-Opening pain relief: pupillometer may cut opioid use after surgery
- Knee replacement patients may skip hospital visits with remote monitoring