PANCREATIC NEOPLASMS

This international study compares two minimally invasive surgery techniques for removing benign or pre-cancerous tumors from the left side of the pancreas. Researchers will randomly assign 256 eligible patients to either laparoscopic (surgeon-controlled instruments) or robot-assi…

This study is testing whether adding two new drugs (TQB2868 and anlotinib) to standard chemotherapy works better for people newly diagnosed with advanced pancreatic cancer. It will involve about 80 participants who have not had prior cancer drug treatment. Researchers will measur…

This study is testing a multi-part treatment for people whose pancreatic cancer has spread to the liver. Doctors deliver chemotherapy and an immunotherapy drug directly into the liver's blood vessels, aiming to target the tumors more effectively. The goal is to see if this approa…

This early-stage study is testing a new type of personalized cell therapy for people with advanced solid tumors, including mesothelioma, that have come back or spread after standard treatments. Doctors collect a patient's own immune cells, genetically modify them in a lab to bett…

This study is testing a procedure that uses heat to destroy solid pancreatic tumors. It is for patients with pancreatic cancer or neuroendocrine tumors who are not suitable candidates for surgery. Doctors use an ultrasound-guided needle to apply radiofrequency energy to heat and …

This study is testing an experimental pill called LY3537982 for people with advanced cancers that have a specific genetic change called KRAS G12C. The research aims to find the safest and most effective dose, both alone and combined with other cancer drugs, for patients with lung…

This early-stage trial is testing a new treatment for advanced pancreatic cancer. Doctors take a patient's own immune cells (T cells), genetically modify them in a lab to recognize and attack cancer cells with a specific KRAS G12V mutation, and then infuse them back into the pati…

This study is testing whether genetic analysis of pancreatic tumors can predict how well patients respond to chemotherapy before surgery. Researchers will give 45 patients with non-metastatic pancreatic cancer a standard chemotherapy combination called FOLFIRINOX, then analyze tu…

This study aims to develop better methods for identifying which pancreatic cysts are likely to become cancerous versus those that are harmless. Researchers will follow 5,000 patients with pancreatic cysts over time to understand how these growths naturally progress. The goal is t…

This study aims to confirm if a new blood test can find pancreatic cancer at its earliest, most treatable stages. Researchers will test the method in 2,000 people, including those with and without pancreatic cancer. The test looks for tiny genetic signals in the blood that may in…

This study is testing if a special ultrasound scan done before pancreas surgery can predict how soft the pancreas tissue is during the operation. A soft pancreas is a known risk factor for a dangerous leak called a pancreatic fistula after surgery. The study will enroll 100 patie…

This large international study is collecting information on a new, more precise type of radiation therapy that uses real-time MRI scans to guide treatment. It aims to see if this advanced technology helps people with many types of cancer live longer, better control their tumors, …

This study aims to collect blood, urine, and tumor samples from up to 1,000 patients with mesothelioma and other related cancers. The purpose is to build a tissue bank for future research to better understand these diseases. Participants will be followed over time to track their …

This study aims to learn more about pancreatic cysts, which are fluid-filled sacs in the pancreas often found by accident on scans. Researchers will follow 4,000 adults with these cysts over time to see which ones stay harmless and which might develop into cancer. The goal is to …