PANCREATIC NEOPLASMS

This study tests a combination of three drugs (surufatinib, sintilimab, and AG) as the first treatment for people with advanced pancreatic cancer that cannot be removed by surgery. The goal is to see if this mix can shrink tumors and delay cancer growth. The trial involves 32 par…

This study tests a new drug called 9-ING-41, given alone or with chemotherapy, in adults with advanced cancers that have stopped responding to standard treatments. The goal is to see if the drug is safe and can help control the cancer. About 350 people with various cancer types, …

This early-stage study tests the safety of a new drug, PF-08046049/SGN-BB228, in people with advanced melanoma and other solid tumors that have spread or are hard to treat. The study involves 41 participants and will look at side effects and the right dose. It is not expected to …

This early-phase study tests a new treatment called EGFR-BATs for people with advanced pancreatic cancer that has not responded to standard chemotherapy. The treatment uses the patient's own immune cells, which are trained in a lab to better attack cancer cells. The main goal is …

This study looks at new ways to diagnose cancer in the bile ducts or pancreas using bile and blood samples. Researchers are testing special markers (like fats, proteins, and genetic material) to see if they can detect cancer more accurately than current methods. About 500 adults …

This study tests whether a small monitoring probe placed near the surgical site can detect internal leaks early after pancreatic cancer surgery. About 200 adults having this operation will be randomly assigned to receive the probe or standard care. The goal is to see if early det…

This study looks at how end-stage kidney disease affects recovery after pancreatic surgery. Researchers will review medical records from 100 patients to see how kidney failure severity and dialysis use impact complications, hospital stay, and costs. The goal is to provide better …