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Engineered immune cells take on Hard-to-Treat cancers

NCT ID NCT06885697

First seen Nov 01, 2025 · Last updated May 30, 2026 · Updated 36 times

Summary

This early-phase study tests a new treatment called TNhYP218 CAR T cells for people with solid tumors that have high levels of a protein called mesothelin, including mesothelioma. Participants' own immune cells are collected, modified in a lab to better attack cancer, and then given back. The goal is to find a safe dose and see if the treatment shrinks tumors.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

colonic neoplasm gastric neoplasm lung neoplasm mesothelioma neoplasm ovarian cancer pancreatic neoplasm thymoma Thymus Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.