LUNG NEOPLASMS

This early-stage study is testing a new type of personalized cell therapy for people with advanced solid tumors, including mesothelioma, that have come back or spread after standard treatments. Doctors collect a patient's own immune cells, genetically modify them in a lab to bett…

This study is testing whether the drug teniposide can help control advanced small cell lung cancer that has worsened despite standard chemotherapy. It is for patients whose cancer has a specific genetic feature called 'c-Myc-driven.' The main goal is to see if the drug shrinks tu…

This study is testing whether mobile low-dose CT scans can effectively detect lung cancer in younger, high-risk smokers. It focuses on people aged 40-54 with a heavy smoking history (30+ pack-years) in North and South Carolina. The goal is to see if starting screening earlier tha…

This study is testing a blood test as a first step before a CT scan for lung cancer screening. The goal is to see if the blood test can accurately identify people who are unlikely to have lung cancer, so they might avoid an unnecessary scan. This could reduce radiation exposure a…

This study is observing how well a robotic system works in real hospitals to help doctors locate and take samples from suspicious spots in the lungs. It will follow 3,000 patients who are already scheduled to have this robotic-assisted biopsy procedure. The main goal is to see ho…

This study is testing a telehealth coaching program designed to help Hispanic smokers make informed decisions about lung cancer screening. Bilingual patient navigators will guide participants through the screening process and help them understand their options. The goal is to see…

This study is testing if a steroid mouthwash can prevent painful mouth sores, a common side effect, in people with advanced breast or lung cancer. Participants will receive a specific cancer drug and use the mouthwash for the first few treatment cycles. The goal is to see if the …

This study aims to develop a new, non-invasive way to monitor lung cancer patients after surgery to see if their cancer might come back. Researchers will collect blood samples from 100 patients who had lung cancer surgery and use artificial intelligence to analyze multiple types …

This study aims to understand why lung cancers stop responding to targeted drug therapies. Researchers will analyze tumor tissue samples from 500 adults with lung or other chest cancers, both before treatment and when the cancer starts growing again. The goal is to identify genet…

This study aims to understand how doctors in Brazil treat patients with advanced non-small cell lung cancer (NSCLC) in real-world settings. Researchers will collect medical record data from 200 patients starting first-line treatment between 2025-2026 and survey about 300 oncologi…

This study tests whether telehealth coaching helps patients make better decisions about lung cancer screening. It involves about 600 current or former smokers aged 50-77 who are eligible for screening. Researchers will compare coaching sessions to standard care to see which leads…

This study is creating a collection of tissue samples from people with lung cancer to support future research. Participants are those undergoing testing or treatment for lung cancer who consent to donate samples. The goal is to help scientists discover ways to detect lung cancer …

This study aims to understand how lung cancer is treated and what it costs the healthcare system in Canada. Researchers will analyze existing health records from 60,000 patients in Alberta and Ontario to see what treatments were used, how long patients lived, and the associated h…

This study aims to create a detailed national picture of lung cancer in Algeria by observing patients in their normal care. It will track about 3,750 adults with lung cancer across 21 hospitals to understand their diagnosis, treatments, and health outcomes. The goal is to gather …

This study aims to see if cancer cells found in the blood (circulating tumor cells) can help doctors choose the right treatment for people with advanced lung cancer. Researchers will collect blood samples from 80 participants to grow these cells in the lab and test how they respo…