LUNG NEOPLASMS

This study is testing a new, non-surgical treatment for people with multiple early-stage lung nodules, which can be precancerous. About 38 participants will use a nebulizer to inhale a gene therapy called Gendicine. Researchers will check if the treatment safely shrinks or elimin…

This study is testing a new medicine called PF-08634404 to see if it can help adults with early-stage non-small cell lung cancer. The medicine will be given either alone or with chemotherapy, depending on whether the cancer can be removed with surgery. Researchers want to see if …

This study is testing whether a new medicine called PF-08634404 works better when given with standard chemotherapy for a rare, aggressive form of lung cancer called transformed small cell lung cancer. The trial will enroll 40 adults who haven't received treatment for this specifi…

This study is testing whether a special fluorescent dye can help doctors see lung cancer more clearly during a standard lung exam called a bronchoscopy. The dye is designed to stick to cancer cells and glow under special light, potentially making suspicious spots easier to identi…

This study is testing a new computer tool that creates a 3D model of a patient's lungs before lung cancer surgery. Doctors will use this model to perform a 'virtual surgery' to predict how well the patient's lungs will work after the real operation. The goal is to give surgeons a…

This study compares two anesthesia approaches for patients having minimally invasive surgery to remove small lung nodules. Researchers want to know if letting patients breathe on their own with pain blocks is as safe as using a breathing tube and ventilator machine. They'll also …

This study aims to learn if analyzing immune cells from a patient's lung fluid, along with a standard tumor marker (PD-L1), can better predict how well someone with advanced lung cancer will respond to treatment. Researchers will collect lung fluid and tumor tissue from 60 patien…