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Can genes predict chemo success in pancreatic cancer?

NCT ID NCT03977233

First seen Oct 31, 2025 · Last updated Jun 16, 2026 · Updated 26 times

Summary

This study looks at how the genetic makeup of pancreatic cancer affects response to a chemotherapy called FOLFIRINOX given before surgery. About 45 adults with non-metastatic pancreatic cancer will receive the chemo, then have their tumors analyzed to see if genetic subtypes (like basal-like or classical) influence how well the cancer shrinks or becomes removable. The goal is to improve disease control and surgical outcomes.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of North Carolina at Chapel Hill Lineberger Comprehensive Cancer Center

    RECRUITING

    Chapel Hill, North Carolina, 27599, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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Conditions

The condition(s) this trial relates to.

malignant pancreatic neoplasm Pancreatic cancer, adult pancreatic neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.