Simple blood test could spot pancreatic cancer before symptoms start
NCT ID NCT07605819
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is testing a new blood test called Enzeavour that looks for tiny signs of pancreatic cancer in healthy people. About 10,000 adults in Japan getting routine checkups will give a blood sample. If the test shows a high score, they will get further imaging to check for cancer. The goal is to see if this test can find pancreatic cancer early, when it's easier to treat.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Enzeavour Pancreatic Cancer Assay (blood test measuring enzyme activity)
- What this could lead to
- If successful, this blood test could become a routine screening tool to catch pancreatic cancer early, when treatment is more likely to work.
- What could go wrong
- This is an early feasibility study, not a final proof. The test may produce false positives or miss some cancers, and results may not apply outside Japan.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 10,000 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Feb 2026
- Expected to finish
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Dec 2028
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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20 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Asymptomatic adults attending participating facilities for routine health checkups, organized cancer screening, or both * Able to understand the study procedures and provide written informed consent before enrollment Exclusion Criteria: * Documented clinical history of pancreatic cancer * Considered unable or unwilling to undergo any required diagnostic imaging modality (MRCP, EUS, or contrast-enhanced CT) after a positive index test result * Any medical, psychological, or social condition that, in the opinion of the principal investigator at each participating site, makes participation inappropriate or compromises study integrity
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Get notified about this study
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
48 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Aichi Medical University Hospital
RECRUITINGNagakute, Aichi-ken, Japan
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C'est la vie Shinbashi Clinic
RECRUITINGItabashi-ku, Tokyo, Japan
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Clinic Green House
RECRUITINGKochi, Kochi, Japan
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Hiroshima University Hospital
RECRUITINGHiroshima, Hiroshima, Japan
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Hotel Okura Kobe Clinic
RECRUITINGKobe, Hyōgo, Japan
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Ibaraki Medical Center
RECRUITINGMito, Ibaraki, Japan
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Isehara Kyodo Hospital
RECRUITINGIsehara, Kanagawa, Japan
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JA Health Management Center Atsugi
RECRUITINGAtsugi, Kanagawa, Japan
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JA Health Management Center Sagamihara
RECRUITINGSagamihara, Kanagawa, Japan
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JA Onomichi General Hospital
RECRUITINGOnomichi, Hiroshima, Japan
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Japanese RedCross Society Kochi Red Cross Hospital
RECRUITINGKochi, Kochi, Japan
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Jichi Medical University Saitama Medical Center
RECRUITINGSaitama, Saitama, Japan
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Kagawa University Hospital
RECRUITINGKita-gun Miki-cho, Kagawa-ken, Japan
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Keijinkai Maruyama Clinic
RECRUITINGSapporo, Hokkaido, Japan
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Kitasato University Hospital
RECRUITINGSagamihara, Kanagawa, Japan
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Kobe University Hospital
RECRUITINGKobe, Hyōgo, Japan
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Kochi Kenshin Clinic
RECRUITINGKochi, Kochi, Japan
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Koganei Tsurukame Clinic
RECRUITINGKoganei, Tokyo, Japan
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Kyoto Industrial Health Association
RECRUITINGKyoto, Kyoto, Japan
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Kyoto University Hospital
RECRUITINGKyoto, Kyoto, Japan
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Matsusaka Medical Association
RECRUITINGMatsusaka, Mie-ken, Japan
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Medical Check Studio Tokyo Ginza Clinic
RECRUITINGChuo-ku, Tokyo, Japan
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Mie Healthcare center
RECRUITINGTsu, Mie-ken, Japan
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Mie University Hospital
RECRUITINGTsu, Mie-ken, Japan
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Miraza Shinjuku Tsurukame Clinic
RECRUITINGShinjuku-ku, Tokyo, Japan
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Mito Kyodo General Hospital
RECRUITINGMito, Ibaraki, Japan
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NEO Healthcare GI Endoscopy Clinic Honmachi
RECRUITINGOsaka, Osaka, Japan
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Nagoya University Hospital
RECRUITINGNagoya, Aichi-ken, Japan
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Nakagami General Chibana Clinic
RECRUITINGOkinawa, Okinawa, Japan
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Nakagami Hospital
RECRUITINGOkinawa, Okinawa, Japan
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Nihon University Itabashi Hospital
RECRUITINGItabashi-ku, Tokyo, Japan
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Obihiro Kosei Hospital
RECRUITINGObihiro, Hokkaido, Japan
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Oita University Hospital
RECRUITINGYufu, Oita Prefecture, Japan
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Okinawa Health Promotion Foundation
RECRUITINGShimajiri-gun Haebaru-cho, Okinawa, Japan
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Public Interest Incorporated Foundation Yamagata Health Promotion Organization
RECRUITINGYamagata, Yamagata, Japan
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Seirei Hamamatsu General Hospital
RECRUITINGHamamatsu, Shizuoka, Japan
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Seirei Preventive Health Care Center
RECRUITINGHamamatsu, Shizuoka, Japan
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Shiga University of Medical Science Hospital
RECRUITINGŌtsu, Shiga, Japan
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Shinjuku Tsurukame Clinic
RECRUITINGShinjuku-ku, Tokyo, Japan
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St. Marianna University School of Medicine Hospital
RECRUITINGKawasaki, Kanagawa, Japan
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Tane Clinic
RECRUITINGOsaka, Osaka, Japan
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Tane General Hospital
RECRUITINGOsaka, Osaka, Japan
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Teine Keijinkai Hospital
RECRUITINGSapporo, Hokkaido, Japan
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The Jikei University Hospital
RECRUITINGMinato-ku, Tokyo, Japan
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Tokyo Women's Medical University Hospital
RECRUITINGShinjuku-ku, Tokyo, Japan
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Wakayama Medical University Hospital
RECRUITINGWakayama, Wakayama, Japan
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Yamagata University Hospital
RECRUITINGYamagata, Yamagata, Japan
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Yokohama City University Medical Center
RECRUITINGYokohama, Kanagawa, Japan
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a Three-Drug combo crack pancreatic Cancer's defenses?
- Can a blood test before pancreatic surgery predict a dangerous leak?
- New chemo cocktail targets pancreatic cancer at every stage
- Bacteria-Based immunotherapy targets pancreatic tumors in first human test
- Can a new radiation machine cut breath holds for cancer patients?
- Two oral drugs join chemotherapy in a bid to shrink pancreatic tumors