PANCREATIC ADENOCARCINOMA

This study tested a combination of three chemotherapy drugs (paclitaxel protein bound, gemcitabine, and cisplatin) in 34 people with metastatic pancreatic cancer that had not been treated before. If the cancer got worse, a fourth drug (paricalcitol) was added. The goal was to see…

This study compared robotic surgery to traditional open surgery for removing tumors in the pancreas and nearby areas. 268 patients took part to see which method led to faster recovery after the operation. The goal was to find out if robotic surgery is as good as or better than op…

This study tested a combination of four drugs (paclitaxel protein bound, gemcitabine, cisplatin, and paricalcitol) given before surgery to people with pancreatic cancer that could be removed or was borderline removable. The goal was to see if this treatment could shrink tumors an…

This study tested whether adding immunotherapy drugs (ipilimumab or nivolumab) to a targeted therapy (niraparib) can help control advanced pancreatic cancer. It included 104 adults whose cancer had not worsened after initial platinum-based chemotherapy. The goal was to see if the…

This study looked at 546 people who had surgery for pancreatic cancer. After surgery, they received chemotherapy with or without an extra drug (erlotinib) and later some also got radiation. The goal was to see if adding these treatments helped people live longer or keep cancer fr…

This study tested several combinations of immunotherapy drugs in 341 people with metastatic pancreatic cancer that had spread. The goal was to see if these combos could shrink tumors and control the disease. Participants were split into two groups: those who had not yet received …

This study tested a new treatment plan for people with advanced pancreatic cancer that has spread. It combined chemotherapy with drugs that change how genes work and boost the immune system. The goal was to see if the combination is safe and can help control the cancer. 75 patien…

This early-phase trial tested a new treatment called CTX131 for adults with several types of advanced solid tumors that had stopped responding to standard therapies. CTX131 uses a patient's own immune cells that are edited with CRISPR technology to target a protein called CD70 on…

This study tested whether it is safe and possible to collect a small blood sample from the portal vein (a major liver blood vessel) during a routine endoscopic ultrasound in 23 people with pancreatic cancer. The goal was to find and count circulating tumor cells (cancer cells tha…

This study looked at small molecules called microRNAs in tissue samples from 57 people with pancreatic cancer. The samples were collected during a routine endoscopic procedure. Researchers wanted to see if certain microRNA patterns are linked to how aggressive the cancer is, how …

This study involved 247 pancreatic cancer patients and used a computer model to analyze CT scans and tumor tissue. The goal was to see if the model could predict how well patients would respond to chemotherapy and their overall outlook. The research was completed and focused on d…

This study looked at whether it is safe and possible to grow mini-tumors (organoids) from pancreatic cancer samples in the lab. 60 patients with pancreatic cancer provided tumor tissue during surgery or biopsy. Researchers then tested different chemotherapy drugs on these organoi…