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Pesticide link to pancreatic cancer investigated in small study

NCT ID NCT04429490

Knowledge-focused Sponsor: CHU de Reims Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at whether organochlorine pesticides, which build up in body fat over time, are more common in people with pancreatic cancer. Researchers compared fat and urine samples from 56 patients undergoing surgery—some with pancreatic cancer and some without. The goal was to see if higher pesticide levels were linked to the disease.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If a link is found, this could point toward environmental risk factors for pancreatic cancer and guide future prevention efforts.
What could go wrong
This is a small, observational study that cannot prove cause and effect. Results may not apply to the general population.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

56 people

The number who actually took part.

Started

Jun 2020

Finished

May 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

inclusion criteria : Cases : * patients diagnosed with a pancreatic adenocarcinoma, all stages allowed * undergoing a surgery allowing to take a 10 grams adipose tissue sample Controls : * patients without a pancreatic neoplasm on a 6 months old CT scan before inclusion * undergoing a surgery allowing to take a 10 grams adipose tissue sample exclusion criteria : Cases : * patients diagnosed with a pancreatic adenocarcinoma developed on IPMN or cystadenoma * patient with a known genetic predisposition increasing pancreatic adenocarcinoma risk * histopathology proof of a mixed neuroendocrine neoplasm * no surgery allowing to take a 10 grams adipose tissue sample Controls : * patients with a pancreatic neoplasm on a 6 months old CT scan before inclusion * no surgery allowing to take a 10 grams adipose tissue sample

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Conditions

The condition(s) this trial relates to.

carcinoma pancreatic adenocarcinoma pancreatic ductal adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Carcinoma Pancreatic ductal

Contacts and locations

Locations

  • Damien JOLLY

    Reims, France

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