CARCINOMA

This study tests whether adding a new oral drug called NRC-2694-A to standard chemotherapy (paclitaxel) can help control advanced head and neck cancer that has worsened after immunotherapy. About 46 patients who have already tried and progressed on drugs like pembrolizumab or niv…

This study is testing a new type of immunotherapy for children and young adults (up to age 21) whose solid tumors have come back or haven't responded to standard treatments. Doctors take a patient's own immune cells (T cells), modify them in a lab to better target a protein calle…

This study is testing a specialized type of radiation called carbon ion radiotherapy for people with liver cancer that has come back or didn't fully respond to a previous treatment called TARE. The goal is to see if this precise radiation can control the tumor while causing fewer…

This study is testing a personalized approach to treatment for people with HPV-linked throat cancer who have had surgery. The goal is to see if a simple blood test can help doctors decide who needs less intense follow-up therapy, aiming to control the cancer while reducing side e…

This study is observing how well the drug vorolanib works and how safe it is for patients with advanced kidney cancer that has spread or cannot be removed by surgery. It involves 39 adults who are receiving vorolanib as their second treatment option. Researchers will track how lo…

This study is testing whether adding a precise form of radiation, called carbon ion radiotherapy, to a standard two-drug treatment helps people with advanced liver cancer. It aims to see if this combination can control the cancer for longer and improve survival compared to the dr…

This study is testing whether virtual reality (VR) relaxation programs can help reduce pain in people with cancer. Researchers will use a special, non-invasive brain scanner to measure pain levels objectively. The goal is to understand how VR distracts the brain from pain and whe…

This study is testing a new artificial intelligence (AI) tool designed to help match people with advanced cancer to suitable clinical trials. It will enroll up to 50,000 patients to see if using this AI system makes it easier for patients to find and join trials. The researchers …

This study is testing a new type of blood test to see if it can detect the return of kidney cancer earlier than current standard scans. It will follow 450 patients who are having surgery for newly diagnosed kidney cancer. Researchers will track changes in genetic markers in the b…

This study is testing a new type of PET scan to see if it can help doctors predict which chemotherapy drugs might work best for a patient's metastatic cancer. A small number of participants with advanced cancer will receive an injection of an experimental imaging agent and then h…

This study is testing a French version of a questionnaire that asks patients about their appearance and quality of life after nasal reconstruction surgery for skin cancer. Researchers want to make sure the translated questionnaire works well and gives reliable information. The re…

This study is a national registry that will follow nearly 2,000 patients in Germany with advanced ovarian or endometrial cancer for up to three years. Its purpose is to document the real-world treatments patients receive, track how the disease progresses, and measure their qualit…

This study is testing a new laboratory method to see if it can predict which cancer treatments will work best for a patient. Researchers will take a sample of a patient's tumor cells from a fluid or tissue biopsy and test how the cells react to different drugs in the lab. The goa…