New pill combo shows promise for tough head and neck cancers
NCT ID NCT05283226
First seen Jan 25, 2026 · Last updated May 22, 2026 · Updated 13 times
Summary
This study tests an experimental oral drug (NRC-2694-A) combined with a standard chemotherapy (paclitaxel) in people with advanced head and neck cancer that has returned or spread and no longer responds to immunotherapy. About 46 adults will receive the combination to see if it can shrink tumors. The goal is to find a new treatment option for this hard-to-treat cancer.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Basavatarakam Indo American Cancer Hospital & Research Institute
NOT_YET_RECRUITINGHyderabad, Telangana, 500034, India
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Dartmouth Hitchcock Medical Center
COMPLETEDLebanon, New Hampshire, 03756-1000, United States
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Daycare Angels under AOH
RECRUITINGMumbai, Maharashtra, 40001, India
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Grant Medical Foundation Ruby Hall Clinic
COMPLETEDPune, Maharashtra, 411001, India
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Los Angeles Hematology Oncology Medical Group
COMPLETEDLos Angeles, California, 90017, United States
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Lynn Cancer Center
COMPLETEDBoca Raton, Florida, 33486, United States
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Miami Cancer Center
COMPLETEDMiami, Florida, 33176, United States
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Norton Cancer Institute - Downtown
COMPLETEDLouisville, Kentucky, 40202, United States
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Providence Medical Foundation -Fullerton
COMPLETEDFullerton, California, 92835, United States
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Salib Oncology
COMPLETEDEaston, Pennsylvania, 18045, United States
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University of Maryland Greenebaum Cancer Center
COMPLETEDBaltimore, Maryland, 21201-1544, United States
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University of Wisconsin Carbone Cancer Center
COMPLETEDMadison, Wisconsin, 53792, United States
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Washington University - Siteman Cancer Center
COMPLETEDSt Louis, Missouri, 63110, United States
Conditions
Explore the condition pages connected to this study.