Blood test may spot kidney cancer return before scans do
NCT ID NCT05917106
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether a simple blood test that finds bits of tumor DNA can help doctors monitor kidney cancer after surgery. Researchers will follow 450 people who have just been diagnosed with kidney cancer and are having surgery to remove it. The goal is to see if the blood test can predict cancer coming back earlier than standard imaging scans.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 450 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Dec 2022
- Expected to finish
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Jun 2030
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
RCC patients undergoing surgical treatment
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Newly diagnosed renal cell carcinoma * Without any treatment * Agree and accept radical surgical treatment * Signed written informed consent * ECOG(Eastern Cooperative Oncology Group) performance is 0 or 1 * Follow up protocol and related procedures Exclusion Criteria: * Had other cancers * Had received any antitumor therapy before * Known or suspected active autoimmune disease * Informed consent is not possible due to medical or psychiatric problems * Have clinical symptoms or diseases of the heart that are not well controlled * Patients judged by the investigators to be unsuitable for inclusion in this study
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China
RECRUITINGNanjing, Jiangsu, 210000, China
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Other studies related to the condition(s) this trial covers.
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- Can a new drug target Hard-to-Treat kidney and ovarian cancers?