New endoscopic technique hunts cancer cells in the portal vein
NCT ID NCT05247164
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether it is safe and possible to collect a blood sample from the portal vein (a major liver blood vessel) during a routine endoscopic ultrasound in 23 people with pancreatic cancer. The goal was to find and count circulating tumor cells (cancer cells in the blood) to learn more about the disease. The study did not offer a treatment, but aimed to improve understanding of how pancreatic cancer spreads.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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23 people
The number who actually took part.
- Started
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May 2022
- Finished
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Mar 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * patient with a pancreatic solid lesion undergoing EUS with a rapid on-site confirmation of a pancreatic ductal adenocarcinoma * patients primarily followed within San Raffaele Institute Exclusion Criteria: * history of active non-pancreatic cancer * coagulopathy (INR \> 1.5; platelets \< 70.000/ul) or use of non-withdrawable anticoagulant or antiplatelet * known history or endosonographic signs of portal hypertension * extensive invasion of portal vein precluding needle maneuvers * pregnancy and breastfeeding
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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IRCCS San Raffaele Scientific Institute
Milan, 20132, Italy
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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