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New hope for Hard-to-Treat gut cancers: first human trial launched

NCT ID NCT05411133

First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 32 times

Summary

This early study tested a new drug called Cabotamig (ARB202) in 33 adults with advanced gastrointestinal cancers (like stomach, liver, or bowel cancer) that had stopped responding to standard treatments. The drug works by targeting a marker called CDH17 on cancer cells and helping the immune system attack them. The main goals were to check safety and how the drug behaves in the body, and to see if it could shrink tumors.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Queen Mary Hospital

    Hong Kong, Hong Kong

  • Southern Oncology Clinical Research Unit

    Adelaide, Australia

  • St George Private Hospital

    Sydney, Australia

Conditions

Explore the condition pages connected to this study.