MALIGNANT SOLID NEOPLASM

This study tested a virtual program that combines weight management with short mindfulness exercises for obese cancer survivors. The goal was to see if it's feasible and can improve mood, stress, and weight. Nineteen adults who had stage I-III cancer and a BMI of 30 or higher too…

This early-phase trial tested a combination of four drugs—entinostat, atezolizumab, carboplatin, and etoposide—in people with extensive-stage small cell lung cancer that had not been treated before. The goal was to find the safest dose and see if the combination could help contro…

This study tested whether adding pembrolizumab (an immunotherapy drug) to radiation therapy can help shrink tumors and slow cancer growth in people with advanced non-small cell lung cancer. 124 participants received either stereotactic or conventional radiation along with the dru…

This study tested the drug pegloticase in 10 cancer patients with high uric acid levels caused by tumor lysis syndrome, a complication where dying cancer cells release substances into the blood. The goal was to see if pegloticase could quickly lower uric acid and protect kidney f…

This study tested a new antibiotic combination (imipenem-relebactam) against standard antibiotics for treating fever caused by low white blood cells in 100 adults with cancer. The goal was to see if the new treatment works better at controlling infections and helps doctors use an…

This study tested new adhesive sensors that stick to the skin to detect early signs of lymphedema, a painful arm swelling that can happen after cancer treatment. Researchers compared 76 people with and without lymphedema to see if the sensors could tell the difference. The goal i…

This study tested a CBD cream against a placebo cream to see if it could reduce nerve pain, numbness, and tingling in the hands and feet caused by chemotherapy. Forty adults with cancer who had moderate to severe nerve pain used the cream daily for four weeks. The goal was to fin…

This study looked at whether increasing physical activity can improve physical functioning and quality of life in cancer survivors who are over 60 or live in rural areas. About 100 participants completed a 12-week virtual exercise program. Researchers measured changes in enduranc…

This pilot study tested whether acupressure, a non-invasive technique using finger pressure on specific body points, can help reduce anxiety in patients receiving chemotherapy. Thirty adults undergoing chemotherapy at Mayo Clinic who reported at least mild anxiety were offered a …

This study looked at whether using electronic health records to track and manage common cancer symptoms—such as pain, fatigue, sleep problems, anxiety, and depression—can improve quality of life and reduce urgent care visits. Over 50,000 cancer patients took part. The goal was to…

This study tested whether a nasal spray made with rose geranium in sesame oil can improve nose symptoms like dryness, discomfort, bleeding, or scabbing in cancer patients receiving chemotherapy. About 106 adults with cancer and nose symptoms joined this phase III trial. Half used…

This study tested whether doing simple positive activities—like helping with household tasks or writing a gratitude letter—could improve quality of life for cancer patients from collectivist cultures (e.g., Latino, Asian American, African American). 75 patients and their caregive…

This study tested whether young cancer survivors (ages 15-39) could learn to press on specific body spots (acupressure) to help with tiredness. 42 people who had finished cancer treatment at least 3 months ago and still felt very tired took part. They were taught how to do acupre…

This study tested a pain management program for 51 cancer survivors living in rural areas or who are Hispanic. The goal was to see if the program was easy to use and helpful for controlling cancer-related pain. Researchers measured how often participants used the program and how …

This study followed 200 adults aged 40-85 with cancer who were about to start chemotherapy. Researchers measured symptoms like numbness, disability, and daily activity to find simple tests that could predict when patients are at higher risk for falls and loss of function. The goa…

This study looked at whether adding a type of antibiotic called aminoglycosides helps cancer patients with sepsis (a severe infection) recover from dangerously low blood pressure. Researchers studied 232 adult cancer patients with sepsis. They compared those who got standard anti…

This study tested a training program for community healthcare providers to improve their knowledge and skills in caring for cancer survivors. 28 providers from Ohio hospitals participated in virtual sessions. The goal was to see if the program increased their comfort and ability …

This study tested a program called GUIDE, where a trained navigator helps cancer patients overcome social and financial barriers to join clinical trials. 100 adults with cancer who were eligible for a trial and had at least one social need (like food or housing issues) took part.…

This study tested whether a wearable device and smartphone app can better track vital signs and symptoms in cancer patients than standard in-clinic checks. About 100 adults with various cancers participated. The goal was to see if remote monitoring could detect complications like…

This study tested whether 3D surface images can be used instead of standard CT scans to plan electron radiation therapy for cancer. Researchers used plastic models (not real patients) to compare the accuracy of 3D scans with CT scans. If successful, this approach could reduce rad…

This study tested a program designed to help adolescent and young adult cancer survivors (ages 15-39) find healthcare resources, learn self-care skills, and get support. The goal was to see if the program could reduce cancer-related distress and help survivors follow recommended …

This study tested a program called Mates in Motion, which helps blood cancer patients and their caregiving partners become more physically active together. The program teaches communication and behavior change skills to support each other in walking and staying active. Researcher…

This study tested a program called FinFit to help adolescent and young adult cancer survivors deal with money problems caused by their illness. Researchers interviewed 16 people from community cancer clinics to understand how to best deliver financial support. The goal was to cre…

This study looked at tumor tissue and blood samples from 141 adults with glioblastoma or other solid tumors. The goal was to measure cell counts and viability to help scientists develop better treatments in the future. Participants were already scheduled for surgery, and the stud…