HIV/AIDS

This study tested a new HIV medication (Biktarvy) taken twice daily in 122 adults with both HIV and tuberculosis (TB). Participants were already on standard TB treatment. The goal was to see if the new pill could control HIV as well as the current standard treatment. Results show…

This study tested a program to help HIV-positive men who have sex with men (MSM) and struggle with substance use feel less shame and stigma about their health. The goal was to help them stay engaged in HIV care. Fifty participants tried the program, and researchers checked if it …

This study tested whether counseling can help people living with HIV in Zambia reduce unhealthy alcohol use and improve their HIV control. About 680 adults were split into three groups: a brief counseling session, brief counseling plus more in-depth therapy, or standard care. The…

This study tested whether a mobile health van, combined with a needle exchange program, could improve HIV prevention and treatment for people who inject drugs. 720 participants were enrolled. The van offered services like HIV testing, treatment, and prevention tools. The goal was…

This pilot study tested whether a problem-solving program delivered by video call or text message could help young adults (ages 18-29) living with HIV stay engaged in care, improve mental health, and reduce substance use. Fifty participants from the East Bay area of San Francisco…

This study looked at how to best manage high blood pressure in people living with HIV in Uganda. Researchers compared two different approaches to add blood pressure care into regular HIV clinic visits. Over 87,000 adults took part, and the goal was to see which method worked bett…

This study tested whether bringing HIV and chronic disease care into the community and linking it with microfinance groups helps people with HIV stay in care and keep the virus under control. About 1,200 adults in rural Kenya took part. The goal was to see if this combined approa…

This study tested whether blocking a hormone called aldosterone and boosting another called BNP can reduce early heart damage in people with HIV. 39 adults with well-controlled HIV and signs of early heart strain took part. The goal was to see if this approach could lower inflamm…

This study tested a short, personalized program called PARTNER for young men who have sex with men (YMSM) in relationships. The program used 4 motivational interviewing sessions to encourage PrEP use, reduce risky sex, and cut down on drug use. 196 participants completed the stud…

This study tested two different HIV medication combinations in 447 people with advanced HIV (late presenters). One group took a newer integrase inhibitor combo (Biktarvy), the other a boosted protease inhibitor combo (Symtuza). The goal was to see which works better and causes fe…

This study looked at 114 HIV-positive adults hospitalized with an additional infection (opportunistic disease). Researchers compared starting antiretroviral therapy (ART) within 48 hours of admission versus waiting until the infection was under control. The goal was to see if imm…

This study tested a mobile app version of an existing program called "Getting Off" to help gay and bisexual men reduce their methamphetamine use and risky sexual behaviors. 226 men who use methamphetamine participated. The app includes games, lessons, and resources to support beh…

This study tested whether giving early treatment for cytomegalovirus (CMV) and tuberculosis (TB) can help HIV-infected infants with severe pneumonia survive. Over 500 babies under one year old were enrolled. The goal was to see if this approach reduces deaths in the short and lon…

This study tested whether delivering support through existing friend groups helps people living with HIV stay in medical care and reduce heavy drinking. Researchers enrolled 341 adults in St. Petersburg, Russia, who were HIV-positive and part of social networks with other HIV-pos…

This study tested a program where pregnant women living with HIV received support from trained peers (other women with HIV) to help them stay in medical care after giving birth. The program included face-to-face sessions during pregnancy and up to three months after delivery. The…

This study tested a short counseling program called Acceptance-Based Behavior Therapy (ABBT) to help people newly diagnosed with HIV stay connected to medical care. The goal was to see if this approach could improve clinic attendance and lower the amount of virus in the blood. Th…

This study tested a mobile app called PeerNaija that sends medication reminders, shows personal and anonymous peer adherence scores, and offers monthly lottery prizes to encourage young people living with HIV in Nigeria to take their medicine regularly. Fifty-four participants ag…

This study tested a smartphone app called LetSync designed to help Black men who have sex with men and their partners stay engaged in HIV care and take their medications as prescribed. About 144 participants (80 couples) used the app for up to 14 months. The goal was to see if th…

This study tested a counseling program called CETA for women with HIV who had experienced intimate partner violence and had unsuppressed virus levels. About 399 women in South Africa took part, receiving either CETA or standard care. The goal was to see if CETA could help more wo…

This study tested a program to help healthcare providers better prescribe HIV PrEP, a daily pill that prevents HIV infection. The program included a web-based tool and a coordinator to support doctors. Ten clinics in San Francisco took part, and the study measured how many PrEP p…

This study tested a program called HUG-M+ designed to help young Thai men who have sex with men get tested for HIV and reduce risky sexual behavior. About 636 men aged 15-29 took part across two cities in northeastern Thailand. The program involved community activities and suppor…

This study tested a phone app designed to help Black young men who have sex with men (ages 18-29) in Alabama get HIV tests and learn about prevention. The app offered education, support, and referrals for PrEP, a daily pill that prevents HIV. Researchers wanted to see if the app …

This study tested whether offering HIV prevention medication (PrEP) to high-risk people in the emergency department could help them start and stay on prevention. 26 adults who were HIV-negative and medically stable took part. The goal was to see if this approach helps overcome ba…

This study tested different support strategies to help young women in South Africa take their daily HIV prevention pills (PrEP) consistently. 360 women aged 18-25 who were sexually active took part. The goal was to find the best way to keep them protected from HIV.

This study tested new ways to help women and men who visit or work at drinking venues in rural Kenya and Uganda start using HIV prevention medication like PrEP. Over 9,000 adults took part, and the program tracked how many began prevention within 4 to 8 weeks. The goal was to mak…

This study tested different ways to deliver HIV testing and counseling to young male couples (ages 15-24) to help them communicate better and reduce risky behaviors. Researchers compared how well each method worked at lowering condomless sex with casual partners and improving com…

This study looked at whether men who have sex with men (MSM) in West Africa would accept and use a daily or on-demand pill (PrEP) to prevent HIV. Over 600 HIV-negative men from Burkina Faso, Côte d'Ivoire, Mali, and Togo took part. They received free PrEP, regular check-ups, and …

This study tested whether an economic empowerment program could reduce alcohol and drug use among adolescents and young adults (ages 15-24) living with HIV in poor communities in Uganda. The 95 participants were already receiving HIV care and had recently used alcohol or drugs. T…

This study tested a simple change in how clinics prescribe TB prevention medicine to people with HIV. Instead of doctors having to choose to prescribe it, the new approach made TB prevention the automatic option unless the doctor decided to opt out. Over 50,000 adults in South Af…

This study tested whether Eye Movement Desensitization and Reprocessing (EMDR) therapy, added to standard HIV care, reduces psychological trauma and improves quality of life in people diagnosed with HIV within the last month. Forty adults were split into two groups: one received …

This study tested two programs to help adolescents aged 10-14 with HIV feel less stigma and shame. One program used group therapy to build coping skills, while the other strengthened family support. The goal was to improve mental health and reduce the negative impact of HIV-relat…

This study tested non-drug methods to reduce nerve pain in the feet and legs of people with HIV. 196 adults with HIV and long-term nerve pain took part. The goal was to see if these approaches could lower pain and improve daily life.

This study looked at how friends and family can help teenagers with HIV stay in care and take their medication regularly. Researchers worked with 60 teens in South Africa to understand which types of support work best. The goal was to find ways to keep teens healthy and reduce th…

This study looked at whether community health workers visiting pregnant women at home in rural South Africa could improve health for both mothers and children. About 1,490 women took part, with some areas getting the home-visit program and others not. Researchers tracked things l…

This study looked at medical records of over 2,000 people with HIV from racial and ethnic minority groups to see if seeing a heart specialist (cardiologist) helps prevent heart disease. Researchers found that those referred to a cardiologist had better heart outcomes. The goal is…

This study looked at how to best prevent tuberculosis (TB) in Malaysian prisons, focusing on inmates with and without opioid dependence. Researchers compared two TB prevention treatments: a standard daily medicine for 40 weeks versus a shorter weekly combination for 12 weeks. The…