HIV/AIDS

This study tests whether using simple, fast tests at the clinic can help people with HIV stick to their medication and keep the virus under control. About 539 people starting HIV treatment in South Africa will get either standard care or extra quick tests for drug levels and viru…

This study tests a program that combines weekly video chats with a counselor and a mobile app to help young adults (ages 18-29) with HIV keep the virus under control. Participants who are not yet virally suppressed will be randomly assigned to either the program or standard care.…

This study tests whether a smartphone app can help community health workers better support people with both TB and HIV in South Africa. The app helps track treatment, remind patients to take medicine, and catch problems early. The goal is to improve treatment success and reduce d…

This study tests if semaglutide, a drug used for diabetes, can reduce harmful belly fat and improve heart health in people with HIV who have extra belly fat. About 108 participants will receive either the drug or a placebo for 32 weeks. The goal is to see if the drug can lower fa…

This study tests a video-based program called VITAL Start for Adolescents to help teens living with HIV take their medicine regularly and keep the virus under control. About 1,800 teens and their caregivers in Malawi will either watch the videos plus get standard care, or just st…

This study tests ways to help teens and young adults with HIV stay engaged in their care. Researchers in Kenya will try text message reminders, peer support, and small cash rewards to prevent missed appointments and improve viral suppression. The goal is to find the most effectiv…

This study tests whether a mix of a DNA vaccine, a booster vaccine, an immune stimulant, and special antibodies can help people with HIV control the virus after stopping their daily antiretroviral therapy. About 11 participants will receive the combination and then pause their re…

This study tests a program to help men who have sex with men in Lima, Peru get HIV testing and connect to treatment or prevention services. The program offers HIV tests at social venues and uses a text-messaging app to share information and support. The goal is to see if this app…

This study tests a web-based program called ORCHID designed to improve mental health and help women with HIV stay in care. It involves 30 aging women of color who also have HPV. Participants learn skills to build positive emotions and resilience through 8 online sessions.

This study compares a shorter course of steroids (8 days for moderate cases, 14 days for severe) against the standard 21-day treatment for Pneumocystis pneumonia (PCP) in people with HIV/AIDS. The goal is to see if the shorter regimen works just as well at preventing death and ma…

This study aimed to see if combining patient surveys, staff training, and telemedicine could improve mental health and substance use care for people living with HIV. The program was planned for adults receiving HIV care at five clinics in Alabama. However, the study was withdrawn…

This study compares two methods of rolling out a program called Bridges, which teaches financial skills and provides support to young people ages 11-17 who lost parents to AIDS. About 1,440 students from 48 schools in Uganda will take part. The goal is to see which method works b…