HEART DISEASES

This study tests whether using an insertable heart monitor to guide early treatment can reduce the amount of time people spend in atrial fibrillation (AFib) after a catheter ablation. About 120 adults with AFib will get a small monitor placed under their skin before or during the…

This study tests whether a civic engagement program can help rural adults improve their heart health. About 2,400 participants will work together to identify and overcome local barriers to healthy eating and physical activity. The goal is to see if this community-driven approach …

This study tests a new device called the PULSTA valve, which is placed inside the heart's pulmonary artery using a thin tube through a blood vessel, avoiding open-heart surgery. It is for people whose pulmonary valve is leaky or narrowed, often due to a birth defect. The study wi…

This study tested whether a risk score, calculated from electronic health records, can help identify people with hidden atrial fibrillation (AF) — a common heart rhythm problem that raises stroke risk. About 1,955 adults aged 30 and older with higher stroke risk scores used a rem…

This study tests whether a nerve block given before heart surgery can reduce pain and the need for strong painkillers like opioids afterward. About 150 adults having certain heart surgeries will receive either a long-lasting or standard numbing medicine. The goal is to see which …

This study follows over 5,000 people with stable heart disease who were previously treated with either an invasive approach (like stents or bypass surgery) plus medications, or medications alone. Researchers want to see which strategy leads to fewer deaths from heart problems or …

This study looks at why South Asians (people from India, Pakistan, Bangladesh, Nepal, and Sri Lanka) living in the US have high rates of heart disease and stroke, even without typical risk factors. Researchers are following over 2,300 adults aged 40-84 to find clues in their heal…

This study examines whether a common gene variation (CYP2C19) influences the long-term risk of major heart problems, strokes, and limb complications in people with blood vessel disease. Researchers will analyze medical records from 13,000 patients who have already had genetic tes…

This study followed nearly 6,000 adults aged 65 and older to learn what factors predict heart disease and stroke. Researchers tracked participants over time to see how risks like high blood pressure or diabetes affect health. The goal was to better understand these conditions in …

This study tests if a phone app called StudyU can help people with heart failure take the right amount of their beta blocker medicine. Five adults aged 65 and older will use the app to see if it's practical and helpful. The goal is to learn if the app is easy to use and fits into…

This study was designed to see if a cholesterol-lowering drug called a PCSK9 inhibitor could also reduce inflammation in the arteries of people with heart disease. Researchers planned to use a special scan to measure inflammation in the aorta. However, the study was withdrawn bef…

This study looks at whether giving doctors a special risk score—which combines a person's genes with things like cholesterol and age—helps them make better decisions to prevent heart disease. About 1000 people at risk for heart disease but who have never had a heart attack will t…

This study watches how over 800 heart failure patients in Germany use the drug dapagliflozin in everyday life. Researchers track treatment changes, symptoms, and quality of life to see how well the drug works outside of controlled trials. No new treatments are tested—just real-wo…

This study looks at whether changing how people connect online can help improve attitudes toward COVID-19 vaccines and related health behaviors. About 4,500 adults in the US with internet access are taking part. Researchers are testing if reducing online segregation and increasin…